ArticleAngewandte Chemie (International ed. in English)2021
Decarboxylative Polyfluoroarylation of Alkylcarboxylic Acids.
Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Radical "Link-and-Lose" Strategies for Iterative C-F Functionalization of Polyfluoroarenes.Chem · 2026Article
- Enantioselective copper-catalysed defluorinative alkylation of polyfluoroarenes with alkenes and 1,3-dienes.Chemical science · 2026Article
- β-Acyloxyl alkenyl amide synthesis via multiple defluorination: α-Trifluoromethyl ketone-amine as synergystic peptide coupling reagent.Science advances · 2025Article
- Deacylative Polyfluoroarylation via C-C Cleavage of Alkyl Ketones.Organic letters · 2025Article
- Aminoalkylation of Alkenes Enabled by Triple Radical Sorting.Journal of the American Chemical Society · 2025Article
- Ligand Relay for Nickel-Catalyzed Decarbonylative Alkylation of Aroyl Chlorides.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Synthetic Advantages of Defluorinative C-F Bond Functionalization.Angewandte Chemie (International ed. in English) · 2023Review
- Copper-catalyzed defluorinative arylboration of vinylarenes with polyfluoroarenes.Chemical science · 2023Article
- Transition metal-free photochemical C-F activation for the preparation of difluorinated-oxindole derivatives.Chemical science · 2023Article
- Visible-light-induced selective defluoroalkylations of polyfluoroarenes with alcohols.Chemical science · 2023Article
- Photoredox Polyfluoroarylation of Alkyl Halides via Halogen Atom Transfer.Organic letters · 2022Article
- Recent Advances in C-F Bond Cleavage Enabled by Visible Light Photoredox Catalysis.Molecules (Basel, Switzerland) · 2021Review
- Photocatalytic Decarboxylative Coupling of Aliphatic N-hydroxyphthalimide Esters with Polyfluoroaryl Nucleophiles.Angewandte Chemie (International ed. in English) · 2021Article
- Decarboxylative Polyfluoroarylation of Alkylcarboxylic Acids.Angewandte Chemie (International ed. in English) · 2021Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polyfluoroarenes are useful building blocks in several areas such as drug discovery, materials, and crop protection. Herein, we report the first polyfluoroarylation of aliphatic carboxylic acids via photoredox decarboxylation. The method proceeds with broad substrate scope and high functional group tolerance. Moreover, small complex molecules such as natural products and drugs can be modified by late-stage modification.
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