Evidence map›Paper›PMID 33481233›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Imaging the Nanoscale Distribution of Phosphoinositides in the Cell Plasma Membrane with Single-Molecule Localization Super-Resolution Microscopy.

Fan Fan, Chen Ji, Xuelin Lou

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Fan FanDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
Chen JiDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
Xuelin LouDepartment of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA. xulou@mcw.edu.
Medical College of Wisconsin · US

Funding

Regulated exocytosis and endocytosis coupling in pancreatic endocrine cellsR01DK093953 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI LOU, XUELIN · 2011 to 2015
$1.6M
Exocytosis-endocytosis coupling at presynaptic terminalsR21NS101584 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI LOU, XUELIN · 2017 to 2018
$416k
NIDDK NIH HHS R01 DK093953NINDS NIH HHS R21 NS101584
6 · The paper itself

Abstract

Phosphoinositides make up only a small fraction of cellular phospholipids yet control cell function in a fundamental manner. Through protein interactions, phosphoinositides define cellular organelle identity and regulate protein function and organization and recruitment at the cytosol-membrane interface. As a result, perturbations on phosphoinositide metabolism alter cell physiology and lead to a wide range of human diseases, including cancer and diabetes. Among seven phosphoinositide members, phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P

Indexed as

AnimalsCell Culture TechniquesCell MembraneHumansMembranesMicroscopy, FluorescencePhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsProtein TransportSingle Molecule ImagingType C PhospholipasesPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsType C PhospholipasesCell signalingdSTORMEndocytosisExocytosisINS-1 cellsInsulin secretionMembrane lipidPALMPtdIns(4,5)P2TIRFM

Identifiers

PMID33481233
PMCPMC12935277
OpenAlexW3122789963

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.