Evidence map›Paper›PMID 33481113›Full record

ArticleWorld journal of urology2021

Association between chronic kidney disease and COVID-19-related mortality in New York.

Nihal E Mohamed, Emma K T Benn, Varuna Astha, Kennedy E Okhawere, Talia G Korn, William Nkemdirim, Ami Rambhia, Olajumoke A Ige, Hassan Funchess, Meredith Mihalopoulos and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  13. Article
  14. Review
  15. Impact of COVID-19 on Kidney of Diabetic Patients.Medicina (Kaunas, Lithuania) · 2022
    Review
  16. COVID-19-Associated Mortality among Kidney Transplant Recipients and Candidates in the United States.Clinical journal of the American Society of Nephrology : CJASN · 2021
    Article
  17. COVID19: the response of the urologist.World journal of urology · 2021
    Article
  18. Observational
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Nihal E Mohamed *Department of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
Emma K T Benn *Department of Population Health Science and Policy, Center for Biostatistics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Varuna AsthaDepartment of Population Health Science and Policy, Center for Biostatistics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Kennedy E OkhawereDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
Talia G KornDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
William NkemdirimDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
Ami RambhiaDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
Olajumoke A IgeDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
Hassan FunchessDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
Meredith MihalopoulosDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
Kirolos N MeilikaDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
Natasha KyprianouDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA.
Ketan K BadaniDepartment of Urology, Icahn School of Medicine at Mount Sinai, 6th Floor, 1425, Madison Ave, New York, NY, 10029, USA. ketan.badani@mountsinai.org.ORCID http://orcid.org/0000-0002-5472-7294
Icahn School of Medicine at Mount Sinai · USTisch Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate mortality risk of CKD patients infected with COVID-19, and assess shared characteristics associated with health disparities in CKD outcome.

methodsWe extracted the data from a case series of 7624 patients presented at Mount Sinai Health System, in New York for testing between 3/28/2020 and 4/16/2020. De-identified patient data set is being produced by the Scientific Computing department and made available to the Mount Sinai research community at the following website: https://msdw.mountsinai.org/ .

resultsOf 7624 COVID-19 patients, 7.8% (n = 597) had CKD on hospital admission, and 11.2% (n = 856) died of COVID-19 infection. CKD patients were older, more likely to have diabetes, hypertension, and chronic obstructive pulmonary disease (COPD), were current or former smokers, had a longer time to discharge, and had worse survival compared to non-CKD patients (p < 0.05). COVID-19 mortality rate was significantly higher in CKD patients (23.1% vs 10.2%) with a 1.51 greater odds of dying (95% CI: 1.19-1.90). Controlling for demographic, behavioral, and clinical covariates, the logistic regression analysis showed significant and consistent effects of CKD, older age, male gender, and hypertension with mortality (p < 0.05).

conclusionCKD was a significant independent predictor of COVID-19 mortality, along with older age, male gender, and hypertension. Future research will investigate the effects of COVID-19 on long-term renal function.

Indexed as

AdultAgedAge FactorsComorbidityCOVID-19Diabetes MellitusFemaleHumansHypertensionMaleMiddle AgedNew YorkPrognosisPulmonary Disease, Chronic ObstructiveRenal Insufficiency, ChronicSARS-CoV-2Chronic kidney diseaseComorbidityCOVID-19MortalityPandemicVirus

Identifiers

PMID33481113
PMCPMC7821175
OpenAlexW3124948866

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.