Evidence map›Paper›PMID 33481103›Full record

ArticleSports medicine - open2021

Screening of Potential Stress Biomarkers in Sweat Associated with Sports Training.

Maria João Nunes, Cristina M Cordas, José J G Moura, João Paulo Noronha, Luís Cobra Branco

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Sports medicine - open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05622188 (HEAT Stress Detection From Personally STandARdized Heat Strain Measurements - The HEATSTAR Pilot Trial), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05622188 completednot on this mapstarted 2022, after this paper: background citation

HEAT Stress Detection From Personally STandARdized Heat Strain Measurements - The HEATSTAR Pilot Trial

TypeobservationalSponsorETH ZurichRan2022 to 2023Enrolled23ConditionsHeat StressArmsElevated ambient heat, Elevated relative humidity, Exertion
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Metabolomics analyses and physical interventions in soccer: a systematic review.Metabolomics : Official journal of the Metabolomic Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maria João NunesLAQV, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, 2829-516, Caparica, Portugal. mjm.nunes@fct.unl.pt.
Cristina M CordasLAQV, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, 2829-516, Caparica, Portugal. c.cordas@fct.unl.pt.ORCID https://orcid.org/0000-0002-7892-8955
José J G MouraLAQV, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, 2829-516, Caparica, Portugal.ORCID https://orcid.org/0000-0002-4726-2388
João Paulo NoronhaLAQV, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, 2829-516, Caparica, Portugal.ORCID https://orcid.org/0000-0002-1515-4518
Luís Cobra BrancoLAQV, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus de Caparica, 2829-516, Caparica, Portugal.ORCID https://orcid.org/0000-0003-2520-1151
Rede de Química e Tecnologia · PT

Funding

Fundação para a Ciência e a Tecnologia PTDC/SAU-SOC/28390/2017Fundação para a Ciência e a Tecnologia UIDB/50006/2020
6 · The paper itself

Abstract

backgroundIntense and continuous physical training in sports is related with psychological and physiological stress, affecting the health and well-being of athletes. The development of non-invasive sampling methodologies is essential to consider sweat as a potential biological fluid for stress biomarker assessment. In the current work, the identification in sweat samples of potential molecules that may be used as stress biomarkers was pursued.

methodsA sweat pool sample from football players after a 90-min intense training game was studied.

resultsAn analysis method using liquid chromatography with detection by tandem mass spectrometry (LC-MSMS) to attain a screening profile of sweat composition is presented. The major focus was on neurotransmitters (e.g. monoamines and metabolites) and other biological molecules related with physical training, such as precursors of biogenic amines (phenylaniline, tyrosine, etc.).

conclusionsThis study allowed the identification of small biomolecules, neurotransmitters and other related molecules in sweat that are potentially associated with stress conditions. The developed methodology intends to contribute to the assessment and study of physical and psychological stress biomarkers related with intense sports using non-invasive methods.

Indexed as

BiomarkersLC-MSMSPhysical trainingStressSweat

Identifiers

PMID33481103
PMCPMC7822976
OpenAlexW3123572987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.