ArticlePediatric nephrology (Berlin, Germany)2021
Is ultrasonography mandatory in all children at their first febrile urinary tract infection?
Article in Pediatric nephrology (Berlin, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- ESR Essentials: renal imaging in children-practice recommendations by the European Society of Paediatric Radiology.European radiology · 2026Guideline
- Clinical predictors to guide additional evaluation after a first febrile urinary tract infection in children.World journal of urology · 2026Article
- Abnormal Ultrasound Findings After a Urinary Tract Infection in Children.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Prediction model for severe vesicoureteral reflux in children with urinary tract infection and/or hydronephrosis.Pediatric nephrology (Berlin, Germany) · 2025Article
- UTI in infants: less is more, together is better.Pediatric nephrology (Berlin, Germany) · 2025Article
- NUM-score: A clinical-analytical model for personalised imaging after urinary tract infections.Acta paediatrica (Oslo, Norway : 1992) · 2024Article
- Conflicting views of physicians and surgeons concerning pediatric urinary tract infection: a comparative review.Pediatric radiology · 2023Review
- Hyponatremia and other potential markers of ultrasound abnormalities after a first febrile urinary tract infection in children.European journal of pediatrics · 2023Article
- Early Renal Ultrasound in Patients with Congenital Solitary Kidney Can Guide Follow-Up Strategy Reducing Costs While Keeping Long-Term Prognostic Information.Journal of clinical medicine · 2022Article
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9 authors at 3 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study investigated whether performing kidney ultrasound (KUS) only in children presenting either a pathogen other than E. coli at their first febrile urinary tract infection (fUTI) or experiencing fUTI recurrence would increase missed diagnoses of kidney anomalies.
methodsPatients aged 2-36 months with fUTI who underwent KUS evaluation from 2 January 2013 to 31 June 2018 were enrolled. Cystourethrography was performed after pathological KUS or recurring fUTIs. Thereafter, we retrospectively assessed the detection rate of kidney anomalies through performing KUS only in patients with atypical pathogen at first fUTI or with recurring fUTIs.
resultsIn 263 patients included, the isolated pathogen was E. coli in 223 cases (84.8%) and atypical in 40 cases (15.2%). KUS detected kidney anomalies in 14/223 (6.3%) of fUTIs caused by E. coli and in 11/40 (27.5%) of fUTIs caused by an atypical pathogen (OR 5.5, 95%CI 2.5-14.5). Cystourethrography was performed in 40 patients and vesicoureteral reflux (VUR) found in 20 cases. None of the high grade VUR diagnoses or other kidney anomalies would have been lost through a different diagnostic protocol that required the presence of an atypical pathogen at the first fUTI or a fUTI recurrence to perform the KUS.
conclusionsA diagnostic protocol that requires presence of an atypical pathogen at the first fUTI or a second episode of fUTI to perform the KUS would allow a reduction in the number of negative ultrasounds with a negligible risk of missed diagnoses of kidney anomalies.
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