Evidence map›Paper›PMID 33481077›Full record

ArticleMedizinische Klinik, Intensivmedizin und Notfallmedizin2022

[Risk stratification nomogram for COVID-19 patients with interstitial pneumonia in the emergency department : A retrospective multicenter study].

N Pfeifer, A Zaboli, L Ciccariello, O Bernhart, C Troi, M Fanni Canelles, C Ammari, A Fioretti, G Turcato

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

N PfeiferNotaufnahme, Krankenhaus Meran (SABES-ASDAA), Via Rossini 5, 39012, Meran, Italien.
A ZaboliNotaufnahme, Krankenhaus Meran (SABES-ASDAA), Via Rossini 5, 39012, Meran, Italien.
L CiccarielloNotaufnahme, Krankenhaus Brixen (SABES-ASDAA), Brixen, Italien.
O BernhartInnere Medizin, Krankenhaus Brixen (SABES-ASDAA), Brixen, Italien.
C TroiLabor- und klinische Pathologie, Krankenhaus Brixen (SABES-ASDAA), Brixen, Italien.
M Fanni CanellesNotaufnahme, Krankenhaus Meran (SABES-ASDAA), Via Rossini 5, 39012, Meran, Italien.
C AmmariNotaufnahme, Krankenhaus Meran (SABES-ASDAA), Via Rossini 5, 39012, Meran, Italien.
A FiorettiNotaufnahme, Krankenhaus Meran (SABES-ASDAA), Via Rossini 5, 39012, Meran, Italien.
G TurcatoNotaufnahme, Krankenhaus Meran (SABES-ASDAA), Via Rossini 5, 39012, Meran, Italien. gianni.turcato@yahoo.it.
Krankenhaus Meran · ITKrankenhaus Brixen · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is currently no reliable method to identify which COVID-19 patients in the emergency department will experience rapid disease progression and death.

aimThe aim of this work is to investigate predictive risk factors for 30-day mortality in COVID-19 (coronavirus disease 2019) patients with interstitial pneumonia using patient history, and clinical and laboratory parameters and to develop a nomogram for risk stratification in the emergency department.

methodsA retrospective, multicenter study was conducted in a cohort of 164 patients with COVID-19 pneumonia in the emergency departments of hospitals in Merano and Bressanone from 1 March 2020 to 31 March 2020. Patients were diagnosed as positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using fluorescence reverse transcription polymerase chain reaction (RT-PCR). A nomogram for risk stratification of 30-day mortality of COVID-19 patients was developed based on the parameters studied.

resultsIn all, 35 (21.3%) of 164 COVID-19 patients with interstitial pneumonia died within 30 days of admission to the emergency department. Multivariate analysis method revealed that cognitive deterioration (odds ratio [OR]: 8.330; p = 0.004), lymphocytopenia (OR: 4.229; p = 0.049), renal function deterioration (OR: 4.841; p = 0.028), peripheral oxygen saturation < 93% (OR: 17.871; p = 0.002), age > 75 years (OR: 2.925; p = 0.032), elevated C‑reactive protein (OR: 6.504; p = 0.005), low monocyte count (OR: 0.504; p = 0.004), and comorbidity (OR 5.862; p = 0.019) were associated with 30-day mortality. Using these eight parameters, a nomogram was developed that showed good discrimination with an area under the ROC curve of 0.937.

conclusionThe initial evaluation of the patient history, and the clinical and laboratory data collected in the emergency department provides important prognostic information for risk stratification of COVID-19 patients in the emergency department and for early identification of patients with risk for critical disease course.

Indexed as

COVID-19Lung Diseases, InterstitialAgedEmergency Service, HospitalHumansNomogramsRetrospective StudiesRisk AssessmentSARS-CoV-2COVID-19COVID-19 PneumoniaEmergency DepartmentNomogramSARS-CoV-2

Identifiers

PMID33481077
PMCPMC7821466
OpenAlexW3121190659

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.