ArticleeLife2021
Scleraxis-lineage cell depletion improves tendon healing and disrupts adult tendon homeostasis.
Abstract read
In one paragraph
Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- The cellular basis of fibrotic tendon healing: now in higher definition.American journal of physiology. Cell physiology · 2026Review
- The Secretome From Mechanically Loaded Myoblasts Enhances Tenocyte-Mediated Wound Healing in a 3D In Vitro Tendon Model.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Therapeutically Induced Modulation of Collagen I-to-III Ratio Three Weeks After Rabbit Achilles Tendon Full Transection.Biology · 2026Article
- AMPKα1 Deficiency in Macrophages Impairs Tendon Regeneration and Tendon Stem Cell Function via TNF-α-FBP2 Signaling.International journal of biological sciences · 2026Article
- Epitenon-derived progenitors drive fibrosis and regeneration after flexor tendon injury in a spatially-dependent manner.Nature communications · 2025Article
- Current cutting-edge omics techniques on musculoskeletal tissues and diseases.Bone research · 2025Review
- Article
- PI3K-Akt signalling regulates Scx-lineage tenocytes and Tppp3-lineage paratenon sheath cells in neonatal tendon regeneration.Nature communications · 2025Article
- Il-6 signaling exacerbates hallmarks of chronic tendon disease by stimulating reparative fibroblasts.eLife · 2025Article
- Pharmacological antagonism of Ccr2+ cell recruitment to facilitate regenerative tendon healing.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Loss ofMatrix biology plus · 2025Article
- Insulin-like growth factor-1 (IGF-1) empowering tendon regenerative therapies.Frontiers in bioengineering and biotechnology · 2025Review
- Loss ofbioRxiv : the preprint server for biology · 2024Article
- Pharmacological Antagonism of Ccr2+ Cell Recruitment to Facilitate Regenerative Tendon Healing.bioRxiv : the preprint server for biology · 2024Article
- Development of a nanoparticle-based tendon-targeting drug delivery system to pharmacologically modulate tendon healing.Science advances · 2024Article
- Understanding Tendon Fibroblast Biology and Heterogeneity.Biomedicines · 2024Review
- Interfacial Tissue Regeneration with Bone.Current osteoporosis reports · 2024Review
- Understanding Fibrous Tissue in the Effective Healing of Rotator Cuff Injury.Journal of surgery and research · 2024Article
- Extracellular Vesicles From Primed Adipose-Derived Stem Cells Enhance Achilles Tendon Repair by Reducing Inflammation and Promoting Intrinsic Healing.Stem cells (Dayton, Ohio) · 2023Article
- Establishing in vivo and ex vivo chick embryo models to investigate fetal tendon healing.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Katherine T BestCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, United States.
Antonion KorcariCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, United States.
Keshia E MoraCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, United States.
Anne Ec NicholsCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, United States.
Samantha N MuscatCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, United States.
Emma KnappCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, United States.
Mark R BuckleyCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, United States.
Alayna E LoiselleCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, United States.ORCID 0000-0002-7548-6653
Funding
Modulation of Insertional Achilles Tendinopathy by Multiaxial Mechanical StrainsR01AR070765 · NIAMS · UNIVERSITY OF ROCHESTER · PI BUCKLEY, MARK RAYMOND · 2017 to 2021
$1.7Ms100a4 Signaling in Fibrotic Diabetic Tendon HealingR01AR073169 · NIAMS · UNIVERSITY OF ROCHESTER · PI LOISELLE, ALAYNA · 2018 to 2022
$1.7MTraining in Musculoskeletal Science: Comprehensive Training in Pain StudiesT32AR076950 · NIAMS · UNIVERSITY OF ROCHESTER · PI Hani A Awad, Laura M Calvi · 2020 to 2026
$1.7MDefining the relationship between attenuated insulin receptor signaling and fibrosis in diabetic tendinopathyK01AR068386 · NIAMS · UNIVERSITY OF ROCHESTER · PI LOISELLE, ALAYNA · 2016 to 2019
$484kCell Specific Effects of Canonical NF-κB Signaling in Tendon HealingF31AR074815 · NIAMS · UNIVERSITY OF ROCHESTER · PI BEST, KATHERINE T · 2019 to 2019
$45kNIAMS NIH HHS F31 AR074815NIAMS NIH HHS K01 AR068386NIAMS NIH HHS K01AR068386NIAMS NIH HHS R01 AR070765NIAMS NIH HHS R01AR070765NIAMS NIH HHS R01 AR073169NIAMS NIH HHS T32 AR076950
Abstract
Despite the requirement for
Indexed as
HomeostasisWound HealingAnimalsBasic Helix-Loop-Helix ProteinsFemaleMaleMiceTendon InjuriesTendonsBasic Helix-Loop-Helix ProteinsScx protein, mousemouseregenerationregenerative medicineScleraxisstem cellstendon
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.