Evidence map›Paper›PMID 33480194›Full record

ArticleJournal of clinical neurology (Seoul, Korea)2021

Treatments for Convulsive and Nonconvulsive Status Epilepticus in Adults: An Expert Opinion Survey in South Korea.

Jung Ick Byun, Dong Wook Kim, Keun Tae Kim, Kwang Ik Yang, Soon Tae Lee, Jong Geun Seo, Young Joo No, Kyung Wook Kang, Daeyoung Kim, Yong Won Cho and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical neurology (Seoul, Korea), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Jung Ick ByunDepartment of Neurology, Kyung Hee University Hospital at Gangdong, Kyung Hee University, School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6224-4575
Dong Wook KimDepartment of Neuroloy, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4484-0602
Keun Tae KimDepartment of Neurology, Keimyung University School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-7124-0736
Kwang Ik YangDepartment of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan, Korea.ORCID https://orcid.org/0000-0001-6343-6520
Soon Tae LeeDepartment of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4767-7564
Jong Geun SeoDepartment of Neurology, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-3944-5731
Young Joo NoDepartment of Neurology, Samsung Noble County, Yongin, Korea.ORCID https://orcid.org/0000-0002-0145-5707
Kyung Wook KangDepartment of Neurology, Chonnam National University Hospital, Chonnam National University School of Medicine, Gwangju, Korea.ORCID https://orcid.org/0000-0001-9362-8670
Daeyoung KimDepartment of Neurology, Chungnam National University Hospital, Daejeon, Korea.ORCID https://orcid.org/0000-0001-9056-0017
Yong Won ChoDepartment of Neurology, Keimyung University School of Medicine, Daegu, Korea. neurocho@gmail.com.ORCID https://orcid.org/0000-0002-6127-1045
Jae Moon KimDepartment of Neurology, Chungnam National University Hospital, Daejeon, Korea. jmoonkim@cnu.ac.kr.ORCID https://orcid.org/0000-0002-5035-9877
Drug Committee of Korean Epilepsy Society
Keimyung University · KRKonkuk University · KRChonnam National University Hospital · KRChungnam National University Hospital · KRKyung Hee University Hospital at Gangdong · KRKyungpook National University · KRSamsung (South Korea) · KRSeoul National University Hospital · KRSoonchunhyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe aim of this study was to survey the expert opinions on treatments for convulsive status epilepticus (CSE) and nonconvulsive status epilepticus (NCSE) in adults.

methodsForty-two South Korean epileptologists participated in this survey. They completed an online questionnaire regarding various patient scenarios and evaluated the appropriateness of medications used to treat CSE and NCSE.

resultsInitial treatment with a benzodiazepine (BZD) followed by either a second BZD or an antiepileptic drug (AED) monotherapy was the preferred treatment strategy. More than two-thirds of the experts used a second BZD when the first one failed, and consensus was reached for 84.8% of the survey items. The preferred BZD was intravenous (IV) lorazepam for the initial treatment of status epilepticus. IV fosphenytoin and IV levetiracetam were chosen for AED monotherapy after the failure of BZD. The treatments for NCSE were similar to those for CSE. Continuous IV midazolam infusion was the treatment of choice for iatrogenic coma in refractory CSE, but other AEDs were preferred over iatrogenic coma in refractory NCSE.

conclusionsThe results of this survey are consistent with previous guidelines, and can be cautiously applied in clinical practice when treating patients with CSE or NCSE.

Indexed as

consensusnonconvulsive status epilepticusstatus epilepticustreatment

Identifiers

PMID33480194
PMCPMC7840316
OpenAlexW3099871644

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.