Evidence map›Paper›PMID 33480193›Full record

ReviewJournal of clinical neurology (Seoul, Korea)2021

Antiepileptic Drug Therapy for Status Epilepticus.

Daeyoung Kim, Jae Moon Kim, Yong Won Cho, Kwang Ik Yang, Dong Wook Kim, Soon Tae Lee, Young Joo No, Jong Geun Seo, Jung Ick Byun, Kyung Wook Kang and 2 more

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of clinical neurology (Seoul, Korea), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Daeyoung KimDepartment of Neurology, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0001-9056-0017
Jae Moon KimDepartment of Neurology, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea. jmoonkim@cnu.ac.kr.ORCID https://orcid.org/0000-0002-5035-9877
Yong Won ChoDepartment of Neurology, Keimyung University School of Medicine, Daegu, Korea. neurocho@gmail.com.ORCID https://orcid.org/0000-0002-6127-1045
Kwang Ik YangDepartment of Neurology, Soonchunhyang University College of Medicine, Cheonan Hospital, Cheonan, Korea.ORCID https://orcid.org/0000-0001-6343-6520
Dong Wook KimDepartment of Neurology, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4484-0602
Soon Tae LeeDepartment of Neurology, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-4767-7564
Young Joo NoDepartment of Neurology, Samsung Noble County, Yongin, Korea.ORCID https://orcid.org/0000-0002-0145-5707
Jong Geun SeoDepartment of Neurology, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID https://orcid.org/0000-0002-3944-5731
Jung Ick ByunDepartment of Neurology, Kyung Hee University Hospital at Gangdong, Seoul, Korea.ORCID https://orcid.org/0000-0002-6224-4575
Kyung Wook KangDepartment of Neurology, Chonnam National University Hospital, Chonnam National University School of Medicine, Gwangju, Korea.ORCID https://orcid.org/0000-0001-9362-8670
Keun Tae KimDepartment of Neurology, Keimyung University School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-7124-0736
Drug Committee of Korean Epilepsy Society
Keimyung University · KRKonkuk University · KRChonnam National University Hospital · KRChungnam National University Hospital · KRKyung Hee University Hospital at Gangdong · KRKyungpook National University · KRSamsung (South Korea) · KRSeoul National University Hospital · KRSoonchunhyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Status epilepticus (SE) is one of the most serious neurologic emergencies. SE is a condition that encompasses a broad range of semiologic subtypes and heterogeneous etiologies. The treatment of SE primarily involves the management of the underlying etiology and the use of antiepileptic drug therapy to rapidly terminate seizure activities. The Drug Committee of the Korean Epilepsy Society performed a review of existing guidelines and literature with the aim of providing practical recommendations for antiepileptic drug therapy. This article is one of a series of review articles by the Drug Committee and it summarizes staged antiepileptic drug therapy for SE. While evidence of good quality supports the use of benzodiazepines as the first-line treatment of SE, such evidence informing the administration of second- or third-line treatments is lacking; hence, the recommendations presented herein concerning the treatment of established and refractory SE are based on case series and expert opinions. The choice of antiepileptic drugs in each stage should consider the characteristics and circumstances of each patient, as well as their estimated benefit and risk to them. In tandem with the antiepileptic drug therapy, careful searching for and treatment of the underlying etiology are required.

Indexed as

anestheticsantiepileptic drugsbenzodiazepinesdrug therapyseizurestatus epilepticus

Identifiers

PMID33480193
PMCPMC7840311
OpenAlexW3103897100

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.