Evidence map›Paper›PMID 33480023›Full record

ArticlePhotochemistry and photobiology2021

Evaluation of Acute Reactions on Mouse Skin Irradiated with 222 and 235 nm UV-C.

Nozomi Yamano, Makoto Kunisada, Aiko Nishiaki-Sawada, Hiroyuki Ohashi, Tatsushi Igarashi, Chikako Nishigori

Abstract read
In one paragraph

Article in Photochemistry and photobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Dermatological effects of acute and long-term UV-C exposure: an in vivo study using a portable mercury lamp.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
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  11. Beneficial Effect ofInternational journal of molecular sciences · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nozomi YamanoDivision of Dermatology, Department of Internal Related, Graduate School of Medicine, Kobe University, Kobe, Japan.
Makoto KunisadaDivision of Dermatology, Department of Internal Related, Graduate School of Medicine, Kobe University, Kobe, Japan.ORCID 0000-0003-2210-6108
Aiko Nishiaki-SawadaUshio Inc., Chiyoda-ku, Tokyo, Japan.
Hiroyuki OhashiUshio Inc., Chiyoda-ku, Tokyo, Japan.
Tatsushi IgarashiUshio Inc., Chiyoda-ku, Tokyo, Japan.
Chikako NishigoriDivision of Dermatology, Department of Internal Related, Graduate School of Medicine, Kobe University, Kobe, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological response and DNA damage following irradiation with shorter wavelengths in the UV-C range were evaluated to investigate the safety at three wavelengths because of the recent emergence of germicidal equipment emitting short-wavelength UV-C for various purposes, including medical uses. To estimate an acceptable safety dose for human skin in the UV-C range, especially short UV-C, we studied the biological effects of 207, 222 and 235 nm UV-C using albino hairless mice and evaluated the inflammatory reactions in the skin. To explore an appropriate indicator to evaluate the biological response, we employed determination of the minimal perceptible response dose (MPRD), by which any subtle cutaneous response; erythema, edema and scale could be observed by visual inspection. Erythema was rarely observed, but edema and scale formation were evident for short UV-C wavelengths. The MPRD at 207, 222 and 235 nm was determined to be > 15, 15 and 2.0 kJ m

Indexed as

SkinAnimalsDisinfectionDNA DamageMiceUltraviolet Rays

Identifiers

PMID33480023
PMCPMC8359381

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.