ArticleJournal of general internal medicine2021
Development of the AL-O-A Score for Delirium Screening in Acute Internal Medicine: a Monocentric Prospective Study.
Article in Journal of general internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Treatment limitation decision in delirium: a secondary analysis of a prospective observational study.BMC medical ethics · 2025Observational
- Neurological diagnostic tests for patients with and without delirium: a prospective observational study.GeroScience · 2024Observational
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDelirium occurs frequently in acute internal medicine wards and may worsen the patient's prognosis; it deserves a fast, systematic screening tool.
objectiveDevelop a delirium screening score for inpatients admitted to acute internal medicine wards.
designA monocentric prospective study between November 2019 and January 2020.
participantsTwo hundred and seventeen adult inpatients. MAIN MEASURES: Within 48 h of hospital admission, physicians administered an index test to participants which explored potential predictors associated with the fluctuation of mental state, inattention, disorganised thinking and altered level of consciousness. On the same day, patients underwent a neuropsychological evaluation (reference standard) to assess for delirium. The score was constructed using a backward stepwise logistic regression strategy. Areas under the receiver operating curves (AUC) and calibration curves were drawn to calculate the score's performance. The score was tested on subgroups determined by age, sex and cognitive status.
resultsThe AL-O-A score ("abnormal or fluctuating ALertness, temporospatial Orientation and off-target Answers") showed excellent apparent (AUC 0.95 (95% CI 0.91-0.99)) and optimism-corrected discrimination (AUC 0.92 (95% CI 0.89-0.96)). It performed equally well in subgroups with and without cognitive impairment (AUC 0.93 (95% CI 0.88-0.99) vs 0.92 (95% CI 0.80-0.99)); in men and women (AUC 0.96 (95% CI 0.94-0.99) vs 0.95 (95% CI 0.89-0.99)); and in patients younger and older than 75 years old (AUC 0.98 (95% CI 0.95-0.99) vs 0.93 (95% CI 0.87-0.99)).
conclusionsA simple, 1-min screening test (AL-O-A score), even administered by an untrained professional, can identify delirium in internal medicine patients.
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