Evidence map›Paper›PMID 33479667›Full record

ArticleRSC medicinal chemistry2020

Radiosynthesis and evaluation of 4-(6-[

Wakana Mori, Tomoteru Yamasaki, Yasushi Hattori, Yiding Zhang, Katsushi Kumata, Masayuki Fujinaga, Masayuki Hanyu, Nobuki Nengaki, Hong Zhang, Ming-Rong Zhang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. The role of neuroimaging in Parkinson's disease.Journal of neurochemistry · 2021
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Wakana MoriDepartment of Advanced Nuclear Medicine Sciences , National Institute of Radiological Sciences , National Institutes for Quantum and Radiological Science and Technology , Anagawa 4-9-1, Inage-ku , Chiba , 263-8555 , Japan . Email: zhang.ming-rong@qst.go.jp.
Tomoteru YamasakiDepartment of Advanced Nuclear Medicine Sciences , National Institute of Radiological Sciences , National Institutes for Quantum and Radiological Science and Technology , Anagawa 4-9-1, Inage-ku , Chiba , 263-8555 , Japan . Email: zhang.ming-rong@qst.go.jp.
Yasushi HattoriDepartment of Advanced Nuclear Medicine Sciences , National Institute of Radiological Sciences , National Institutes for Quantum and Radiological Science and Technology , Anagawa 4-9-1, Inage-ku , Chiba , 263-8555 , Japan . Email: zhang.ming-rong@qst.go.jp.
Yiding ZhangDepartment of Advanced Nuclear Medicine Sciences , National Institute of Radiological Sciences , National Institutes for Quantum and Radiological Science and Technology , Anagawa 4-9-1, Inage-ku , Chiba , 263-8555 , Japan . Email: zhang.ming-rong@qst.go.jp.
Katsushi KumataDepartment of Advanced Nuclear Medicine Sciences , National Institute of Radiological Sciences , National Institutes for Quantum and Radiological Science and Technology , Anagawa 4-9-1, Inage-ku , Chiba , 263-8555 , Japan . Email: zhang.ming-rong@qst.go.jp.
Masayuki FujinagaDepartment of Advanced Nuclear Medicine Sciences , National Institute of Radiological Sciences , National Institutes for Quantum and Radiological Science and Technology , Anagawa 4-9-1, Inage-ku , Chiba , 263-8555 , Japan . Email: zhang.ming-rong@qst.go.jp.
Masayuki HanyuDepartment of Advanced Nuclear Medicine Sciences , National Institute of Radiological Sciences , National Institutes for Quantum and Radiological Science and Technology , Anagawa 4-9-1, Inage-ku , Chiba , 263-8555 , Japan . Email: zhang.ming-rong@qst.go.jp.
Nobuki NengakiDepartment of Advanced Nuclear Medicine Sciences , National Institute of Radiological Sciences , National Institutes for Quantum and Radiological Science and Technology , Anagawa 4-9-1, Inage-ku , Chiba , 263-8555 , Japan . Email: zhang.ming-rong@qst.go.jp.
Hong ZhangDepartment of Nuclear Medicine and Medical PET Center , The Second Hospital of Zhejiang University School of Medicine , 88 Jiefang Rd , Hangzhou , Hangzhou 310009 , China . Email: hzhang21@zju.edu.cn.
Ming-Rong ZhangDepartment of Advanced Nuclear Medicine Sciences , National Institute of Radiological Sciences , National Institutes for Quantum and Radiological Science and Technology , Anagawa 4-9-1, Inage-ku , Chiba , 263-8555 , Japan . Email: zhang.ming-rong@qst.go.jp.ORCID 0000-0002-3001-9605
National Institutes for Quantum Science and Technology · JPHangzhou Academy of Agricultural Sciences · CNJapan Proton Accelerator Research Complex · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations that increase leucine-rich repeat kinase 2 (LRRK2) activity in the brain are associated with Parkinson's disease. Here, we synthesized a novel compound 4-(6-fluoro-4-(5-isopropoxy-1

Identifiers

PMID33479667
PMCPMC7649847
OpenAlexW3027630642

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.