Evidence map›Paper›PMID 33479636›Full record

ArticleRSC medicinal chemistry2020

The synthesis and biological evaluation of sanguinarine derivatives as anti-non-small cell lung cancer agents.

Liang Jiang, Xiaolu Wang, Yuting Wang, Fang Xu, Zhang Zhang, Ke Ding, Xiaoyun Lu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liang JiangInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE) , School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China . Email: luxy2016@jnu.edu.cn.
Xiaolu WangInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE) , School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China . Email: luxy2016@jnu.edu.cn.
Yuting WangInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE) , School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China . Email: luxy2016@jnu.edu.cn.
Fang XuInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE) , School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China . Email: luxy2016@jnu.edu.cn.
Zhang ZhangInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE) , School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China . Email: luxy2016@jnu.edu.cn.
Ke DingInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE) , School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China . Email: luxy2016@jnu.edu.cn.ORCID 0000-0001-9016-812X
Xiaoyun LuInternational Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE) , School of Pharmacy , Jinan University , 601 Huangpu Avenue West , Guangzhou 510632 , China . Email: luxy2016@jnu.edu.cn.ORCID 0000-0001-7931-6873

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel series of sanguinarine (SA) derivatives were synthesized and evaluated as anti-non-small cell lung cancer (NSCLC) agents. The compounds inhibited A549 and H1975 NSCLC cells with IC

Identifiers

PMID33479636
PMCPMC7489057

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.