Evidence map›Paper›PMID 33479607›Full record

ArticleRSC medicinal chemistry2020

Meridianin D analogues possess antibiofilm activity against

Sara M Brackett, Karlie E Cox, Samantha L Barlock, William M Huggins, David F Ackart, Randall J Bassaraba, Roberta J Melander, Christian Melander

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. A Review: Meridianins and Meridianins Derivatives.Molecules (Basel, Switzerland) · 2022
    Review
  4. [Materials for Selective Inhibition ofSichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
    Review
  5. 2-Aminoimidazoles InhibitInternational journal of molecular sciences · 2022
    Article
  6. Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara M BrackettDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , IN 46556 , USA . Email: cmelande@nd.edu.
Karlie E CoxDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , IN 46556 , USA . Email: cmelande@nd.edu.
Samantha L BarlockDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , IN 46556 , USA . Email: cmelande@nd.edu.
William M HugginsDepartment of Chemistry , North Carolina State University , Raleigh , NC 27695 , USA.
David F AckartDepartment of Microbiology, Immunology, and Pathology , Colorado State University , Fort Collins , CO 80523 , USA.
Randall J BassarabaDepartment of Microbiology, Immunology, and Pathology , Colorado State University , Fort Collins , CO 80523 , USA.
Roberta J MelanderDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , IN 46556 , USA . Email: cmelande@nd.edu.
Christian MelanderDepartment of Chemistry and Biochemistry , University of Notre Dame , Notre Dame , IN 46556 , USA . Email: cmelande@nd.edu.ORCID 0000-0001-8271-4696

Funding

Disrupting Biofilm Formation to Improve TB Drug TreatmentR01AI106733 · NIAID · COLORADO STATE UNIVERSITY · PI BASARABA, RANDALL J · 2013 to 2017
$2.3M
NIAID NIH HHS R01 AI106733
6 · The paper itself

Abstract

The formation of bacterial biofilms significantly decreases the efficacy of antibiotic treatments. Herein, we've investigated the antibiofilm properties of the natural product meridianin D and a library of analogues against

Identifiers

PMID33479607
PMCPMC7523022

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.