ArticleScientific reports2021
A retrospective clinical analysis of pediatric paragonimiasis in a Chinese children's hospital from 2011 to 2019.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Infection and biogeographical characteristics of Paragonimus westermani and P. skrjabini in humans and animal hosts in China: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2024Pooled it
- Stage-specific remodeling of the pulmonary microenvironment during Paragonimus proliferus infection in a rat model.PLoS neglected tropical diseases · 2026Article
- Imported Pediatric Paragonimiasis in China: Two Cases From Zhaotong to Hangzhou.The American journal of case reports · 2026Article
- Mediastinal mass as an unusual presentation of paragonimiasis in a child: a case report and review of diagnostic challenges.BMC infectious diseases · 2026Review
- Atypical subcutaneous nodule-type paragonimiasis in 3 children: case series.Frontiers in surgery · 2026Article
- Imported Familial Pulmonary and Cerebral Paragonimiasis in Korea: Cases and Literature Review from a Clinical Grand Round Conference.Infection & chemotherapy · 2025Review
- IgG4 elevation dilemma at the crossroads of helminth infection and IgG4-related disease: insights from a case report of pediatric paragonimiasis with persistent pericardial effusion.Translational pediatrics · 2025Article
- Chronic pulmonary paragonimiasis in an indigenous Kichwa child infected in the Ecuadorian AmazonBiomedica : revista del Instituto Nacional de Salud · 2025Article
- Analysis of clinical characteristics of 213 clinically diagnosed pediatric patients with paragonimiasis from Yunnan, China.BMC infectious diseases · 2025Article
- Unusual pediatric lung infections: imaging findings.Pediatric radiology · 2024Review
- Paragonimiasis.Advances in experimental medicine and biology · 2024Review
- Pediatric paragonimiasis: a retrospective analysis of cases from a county in south-west China.Frontiers in pediatrics · 2023Article
- Lung flukes of the genusParasitology · 2022Review
- Cerebral paragonimiasis: Clinicoradiological features and serodiagnosis using recombinant yolk ferritin.PLoS neglected tropical diseases · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
Abstract
Diagnosis of pediatric paragonimiasis is difficult because of its non-specific clinical manifestations. We retrospectively reviewed the records of pediatric paragonimiasis in Children's Hospital of Fudan University from January 2011 to May 2019. The confirmed diagnosis of paragonimiasis was based on positive anti-parasite serological tests from the local Center for Disease Control (CDC). A total of 11 patients (mean age: 7.7 ± 3.1, male-female ratio: 7:4) diagnosed as paragonimiasis were included. 81.8% were from endemic areas such as Sichuan and Yunnan, and 36% had a clear history of raw crab or crayfish consumption. The characteristic clinical features of pediatric paragonimiasis were eosinophilia (100%), pleural effusion (81.8%), hepatomegaly (54.5%), ascites (54.5%), and subcutaneous nodules (45.5%). Misdiagnosed with other diseases including tuberculosis (18.2%), pneumonia (9.1%), intracranial space-occupying lesions (9.1%) and brain abcess (9.1%) led to rehospitalization and prolonged hospitalization. For treatment, a 3-day course of 150 mg/kg praziquantel (PZQ) didn't show ideal treatment effectivity and 63.6% needed more than one course of PZQ, while triclabendazole in a total dose of 10 mg/kg had a better efficacy to stubborn manifestations. This study indicated that pediatric paragonimiasis was often misdiagnosed, and the treatment with a 3-day course of 150 mg/kg PZQ had a high rate of failure.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.