ArticleScientific reports2021
Multiparametric ultrasound findings in acute kidney failure due to rare renal cortical necrosis.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 14 citations in OpenAlex.
- Diagnostic value of multi-parameter ultrasound evaluation in sepsis complicated by acute kidney injury.Renal failure · 2024Article
- Ultrasonographic Renal Subcapsular Thickening in Cats with Primary and Metastatic Carcinoma.Veterinary sciences · 2024Article
- Infarcts and ischemia in the abdomen: an imaging perspective with an emphasis on cross-sectional imaging findings.Abdominal radiology (New York) · 2023Review
- Solitaire AB stent mechanical embolization combined with catheter contact thrombolysis for acute renal artery embolism: A case report.Nephrology (Carlton, Vic.) · 2023Article
- Efficacy Evaluation of Ultrasound with Active Contour Model for Hemodialysis in Children with Renal Failure.Computational and mathematical methods in medicine · 2022Article
- Diagnostic value of contrast-enhanced ultrasound in intravenous leiomyomatosis: a single-center experiences.Frontiers in oncology · 2022Article
- Role of Contrast-Enhanced Ultrasound (CEUS) in Native Kidney Pathology: Limits and Fields of Action.Diagnostics (Basel, Switzerland) · 2021Review
- Sono-graphic Rim Sign in Postpartum Renal Cortical Necrosis: Experience at a Tertiary Care Centre.Indian journal of nephrologyArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Renal cortical necrosis (RCN) is a rare cause of acute kidney failure and is usually diagnosed on the basis of characteristic enhancement patterns on cross-sectional imaging. Contrast-enhanced ultrasound (CEUS) offers benefits in patients with kidney failure in the clinical setting including the use of a nonnephrotoxic intravascular contrast agent and the fact that it can be performed at the bedside in critical cases. Therefore, the aim of this study is to investigate whether CEUS can reliably identify typical imaging features of RCN. We retrospectively analyzed 12 patients with RCN examined in our department and confirmation of the diagnosis by either histopathology, other contrast-enhanced cross-sectional imaging tests, and/or CEUS follow-up. Assessed parameters in conventional US were reduced echogenicity, loss of corticomedullary differentiation, length and width of kidney, hypoechoic rim, resistance index and in CEUS delayed wash-in of contrast agent (> 20 s), reverse rim sign, maximum nonenhancing rim and additional renal infarction. Furthermore, imaging features in RCN were compared with the findings in renal vein thrombosis (RVT), among them echogenicity, corticomedullar differentiation, hypoechoic rim, RI value, delayed cortical enhancement, total loss of cortical perfusion and enhancement of renal medulla. All 12 patients showed the reverse rim sign, while a hypoechogenic subcapsular rim was only visible in four patients on B-mode ultrasound. A resistance index (RI) was available in 10 cases and was always less than 1. RI was a strong differentiator in separating RVT from RCN (RI > 1 or not measurable due to hypoperfusion as differentiator, p = 0.001). CEUS showed total loss of medullary enhancement in all cases of RVT. With its higher temporal resolution, CEUS allows dynamic assessment of renal macro- and microcirculation and identification of the typical imaging findings of RCN with use of a nonnephrotoxic contrast agent.
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