ArticleScientific reports2021
Rhizobia use a pathogenic-like effector to hijack leguminous nodulation signalling.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 63 citations in OpenAlex.
- Type III effectors of symbiotic Rhizobia include diverse predicted transcriptional and post-transcriptional modulators.PLoS biology · 2026Article
- Genomic and Functional Characterization of the EndophyticMicroorganisms · 2026Article
- A rhizobium-induced FT-FD module locally activates nodule stem cell gene to promote nodulation.Nature communications · 2026Article
- Coordination of PTI and ETI in legume-rhizobium mutualism.aBIOTECH · 2026Review
- Bradyrhizobium dasycarpae sp. nov. a novel rhizobial species lacking canonical nod genes, isolated from the Moroccan endemic legume Retama dasycarpa.Antonie van Leeuwenhoek · 2026Article
- Article
- Mobile gene clusters and coexpressed plant-rhizobium pathways drive partner quality variation in symbiosis.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The rhizobial type III effectors ErnA and Sup3 hijack the SUMOylation pathway to trigger nodule formation in Aeschynomene species.The New phytologist · 2025Article
- Putative type III effector SkP48 of Bradyrhizobium sp. DOA9 encoding a SUMO protease blocks nodulation in Vigna radiata.Scientific reports · 2025Article
- Utilizing plant synthetic biology to accelerate plant-microbe interactions research.Biodesign research · 2025Review
- Enacting partner specificity in legume-rhizobia symbioses.aBIOTECH · 2025Review
- Regulation of Root Nodule Symbiosis by Soybean Rj Genotypes and Rhizobial Effectors.Microbes and environments · 2025Review
- The Type III Effector NopM from Bradyrhizobium elkanii USDA61 Induces a Hypersensitive Response in Lotus japonicus Root Nodules.Microbes and environments · 2025Article
- The type III effector NopL interacts with GmREM1a and GmNFR5 to promote symbiosis in soybean.Nature communications · 2024Article
- Broad-spectrum ubiquitin/ubiquitin-like deconjugation activity of the rhizobial effector NopD from Bradyrhizobium (sp. XS1150).Communications biology · 2024Article
- Stable composition of gut microbiome in the Asian ladybeetle Coccinella septempunctata reared on natural and artificial diets.Scientific reports · 2024Article
- NopAA and NopD Signaling Association-Related GeneInternational journal of molecular sciences · 2023Article
- NopC/T/L Signal Crosstalk GeneInternational journal of molecular sciences · 2023Article
- Induction and suppression of gene silencing in plants by nonviral microbes.Molecular plant pathology · 2023Review
- Widespread Bradyrhizobium distribution of diverse Type III effectors that trigger legume nodulation in the absence of Nod factor.The ISME journal · 2023Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
Abstract
Legume plants form a root-nodule symbiosis with rhizobia. This symbiosis establishment generally relies on rhizobium-produced Nod factors (NFs) and their perception by leguminous receptors (NFRs) that trigger nodulation. However, certain rhizobia hijack leguminous nodulation signalling via their type III secretion system, which functions in pathogenic bacteria to deliver effector proteins into host cells. Here, we report that rhizobia use pathogenic-like effectors to hijack legume nodulation signalling. The rhizobial effector Bel2-5 resembles the XopD effector of the plant pathogen Xanthomonas campestris and could induce nitrogen-fixing nodules on soybean nfr mutant. The soybean root transcriptome revealed that Bel2-5 induces expression of cytokinin-related genes, which are important for nodule organogenesis and represses ethylene- and defense-related genes that are deleterious to nodulation. Remarkably, Bel2-5 introduction into a strain unable to nodulate soybean mutant affected in NF perception conferred nodulation ability. Our findings show that rhizobia employ and have customized pathogenic effectors to promote leguminous nodulation signalling.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.