ArticleScientific reports2021
Recording site placement on planar silicon-based probes affects signal quality in acute neuronal recordings.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
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- A comparative study assessing neural recording quality and inflammatory tissue response between stiff and flexible microelectrode arrays.Biomaterials · 2026Article
- Multi-scale imaging and recording of in-vivo neural activity.BMB reports · 2026Review
- Optimal inter-electrode distances for maximizing single unit yield per electrode in neural recordings.Microsystems & nanoengineering · 2026Article
- Robust minimally-invasive microfabricated stainless steel neural interfaces for high resolution recording.Nature communications · 2026Article
- Chronic Probing of Deep Brain Neuronal Activity Using Nanofibrous Smart Conducting Hydrogel-Based Brain-Machine Interface Probes.Small science · 2025Article
- Chronic implantable flexible serpentine probe reveals impaired spatial coding of place cells in epilepsy.National science review · 2025Article
- Cracking modes and force dynamics in the insertion of neural probes into hydrogel brain phantom.Journal of neural engineering · 2024Article
- The ultra-thin, minimally invasive surface electrode array NeuroWeb for probing neural activity.Nature communications · 2023Article
- An Ultraflexible Electrode Array for Large-Scale Chronic Recording in the Nonhuman Primate Brain.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Advancing the interfacing performances of chronically implantable neural probes in the era of CMOS neuroelectronics.Frontiers in neuroscience · 2023Review
- Manufacturing Processes of Implantable Microelectrode Array for In Vivo Neural Electrophysiological Recordings and Stimulation: A State-Of-the-Art Review.Journal of micro- and nano-manufacturing · 2022Article
- In Vivo Penetrating Microelectrodes for Brain Electrophysiology.Sensors (Basel, Switzerland) · 2022Review
- Engineering strategies towards overcoming bleeding and glial scar formation around neural probes.Cell and tissue research · 2022Review
- From End to End: Gaining, Sorting, and Employing High-Density Neural Single Unit Recordings.Frontiers in neuroinformatics · 2022Review
- Dataset of cortical activity recorded with high spatial resolution from anesthetized rats.Scientific data · 2021Article
- Assessing the Feasibility of DevelopingFrontiers in neuroscience · 2021Article
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Authors and funding
7 authors.
Funding
Abstract
Multisite, silicon-based probes are widely used tools to record the electrical activity of neuronal populations. Several physical features of these devices are designed to improve their recording performance. Here, our goal was to investigate whether the position of recording sites on the silicon shank might affect the quality of the recorded neural signal in acute experiments. Neural recordings obtained with five different types of high-density, single-shank, planar silicon probes from anesthetized rats were analyzed. Wideband data were filtered to extract spiking activity, then the amplitude distribution of samples and quantitative properties of the recorded brain activity (single unit yield, spike amplitude and isolation distance) were compared between sites located at different positions of the silicon shank, focusing particularly on edge and center sites. Edge sites outperformed center sites: for all five probe types there was a significant difference in the signal power computed from the amplitude distributions, and edge sites recorded significantly more large amplitude samples both in the positive and negative range. Although the single unit yield was similar between site positions, the difference in spike amplitudes was noticeable in the range corresponding to high-amplitude spikes. Furthermore, the advantage of edge sites slightly decreased with decreasing shank width. Our results might aid the design of novel neural implants in enhancing their recording performance by identifying more efficient recording site placements.
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