Evidence map›Paper›PMID 33479218›Full record

ArticleNature communications2021

White pupae phenotype of tephritids is caused by parallel mutations of a MFS transporter.

Christopher M Ward, Roswitha A Aumann, Mark A Whitehead, Katerina Nikolouli, Gary Leveque, Georgia Gouvi, Elisabeth Fung, Sarah J Reiling, Haig Djambazian, Margaret A Hughes and 14 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
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  3. Review
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  6. Review
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  14. Decoding and engineering temperature-sensitive lethality inProceedings of the National Academy of Sciences of the United States of America · 2025
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  15. Article
  16. Identification and functional characterization of major geneApplied and environmental microbiology · 2025
    Article
  17. Article
  18. Article
  19. New Insight into Nucleotide Changes on IrradiatedTropical life sciences research · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 9 institutions in 8 countries.

Christopher M Ward *School of Biological Sciences, University of Adelaide, 5005, Adelaide, Australia.ORCID 0000-0003-0227-0189
Roswitha A Aumann *Department of Insect Biotechnology in Plant Protection, Justus-Liebig-University Gießen, Institute for Insect Biotechnology, Winchesterstr. 2, 35394, Gießen, Germany.
Mark A WhiteheadCentre for Genomic Research, Institute of Integrative Biology, The Biosciences Building, Crown Street, L69 7ZB, Liverpool, United Kingdom.
Katerina NikolouliInsect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Seibersdorf, 1400, Vienna, Austria.ORCID 0000-0003-4194-0368
Gary LevequeMcGill University Genome Centre, McGill University, Montreal, QC, Canada.
Georgia GouviInsect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Seibersdorf, 1400, Vienna, Austria.ORCID 0000-0002-2274-1622
Elisabeth FungSchool of Biological Sciences, University of Adelaide, 5005, Adelaide, Australia.
Sarah J ReilingMcGill University Genome Centre, McGill University, Montreal, QC, Canada.
Haig DjambazianMcGill University Genome Centre, McGill University, Montreal, QC, Canada.
Margaret A HughesCentre for Genomic Research, Institute of Integrative Biology, The Biosciences Building, Crown Street, L69 7ZB, Liverpool, United Kingdom.
Ivy WhitefordCentre for Genomic Research, Institute of Integrative Biology, The Biosciences Building, Crown Street, L69 7ZB, Liverpool, United Kingdom.
Carlos Caceres-BarriosInsect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Seibersdorf, 1400, Vienna, Austria.
Thu N M NguyenSchool of Biological Sciences, University of Adelaide, 5005, Adelaide, Australia.ORCID 0000-0002-2138-4707
Amanda ChooSchool of Biological Sciences, University of Adelaide, 5005, Adelaide, Australia.ORCID 0000-0002-4510-3615
Peter CrispSchool of Biological Sciences, University of Adelaide, 5005, Adelaide, Australia.
Sheina B SimUSDA-ARS Daniel K. Inouye US Pacific Basin Agricultural Research Center, 64 Nowelo Street, Hilo, HI, 96720, USA.ORCID 0000-0003-0914-6914
Scott M GeibUSDA-ARS Daniel K. Inouye US Pacific Basin Agricultural Research Center, 64 Nowelo Street, Hilo, HI, 96720, USA.
František MarecBiology Centre, Czech Academy of Sciences, Institute of Entomology, Branišovská 31, 370 05, České Budějovice, Czech Republic.ORCID 0000-0002-6745-5603
Irina HäckerDepartment of Insect Biotechnology in Plant Protection, Justus-Liebig-University Gießen, Institute for Insect Biotechnology, Winchesterstr. 2, 35394, Gießen, Germany.ORCID 0000-0003-4022-4853
Jiannis RagoussisMcGill University Genome Centre, McGill University, Montreal, QC, Canada.ORCID 0000-0002-8515-0934
Alistair C DarbyCentre for Genomic Research, Institute of Integrative Biology, The Biosciences Building, Crown Street, L69 7ZB, Liverpool, United Kingdom.
Kostas BourtzisInsect Pest Control Laboratory, Joint FAO/IAEA Programme of Nuclear Techniques in Food and Agriculture, Seibersdorf, 1400, Vienna, Austria. k.bourtzis@iaea.org.
Simon W BaxterBio21 Molecular Science and Biotechnology Institute, School of BioSciences, University of Melbourne, Melbourne, 3010, Australia. simon.baxter@unimelb.edu.au.ORCID 0000-0001-5773-6578
Marc F ScheteligDepartment of Insect Biotechnology in Plant Protection, Justus-Liebig-University Gießen, Institute for Insect Biotechnology, Winchesterstr. 2, 35394, Gießen, Germany. marc.schetelig@agrar.uni-giessen.de.ORCID 0000-0002-9217-394X
International Atomic Energy Agency · ATMcGill Genome Centre · CAUniversity of Liverpool · GBJustus-Liebig-Universität Gießen · DEThe University of Adelaide · AUDaniel K. Inouye U.S. Pacific Basin Agricultural Research Center · USThe University of Melbourne · AUCzech Academy of Sciences · CZSouth Australian Research and Development Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mass releases of sterilized male insects, in the frame of sterile insect technique programs, have helped suppress insect pest populations since the 1950s. In the major horticultural pests Bactrocera dorsalis, Ceratitis capitata, and Zeugodacus cucurbitae, a key phenotype white pupae (wp) has been used for decades to selectively remove females before releases, yet the gene responsible remained unknown. Here, we use classical and modern genetic approaches to identify and functionally characterize causal wp

Indexed as

MutationAmino Acid SequenceAnimalsBase SequenceCeratitis capitataCRISPR-Cas SystemsFemaleFertilityGenome, InsectInsect ProteinsMalePest Control, BiologicalPhenotypePupaReproductionTephritidaeInsect Proteins

Identifiers

PMID33479218
PMCPMC7820335
OpenAlexW3125727830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.