Evidence map›Paper›PMID 33479214›Full record

ArticleScientific data2021

An empirical meta-analysis of the life sciences linked open data on the web.

Maulik R Kamdar, Mark A Musen

Abstract read
In one paragraph

Article in Scientific data, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Programmatic access to ICTV virus taxonomy through a public ontology API.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Metadata integrity in bioinformatics: Bridging the gap between data and knowledge.Computational and structural biotechnology journal · 2023
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Maulik R KamdarCenter for Biomedical Informatics Research, Stanford University, Stanford, CA, USA. maulik@maulik-kamdar.com.ORCID http://orcid.org/0000-0002-9898-0515
Mark A MusenCenter for Biomedical Informatics Research, Stanford University, Stanford, CA, USA.ORCID http://orcid.org/0000-0003-3325-793X

Funding

STANFORD COMPOSITE(RMI)U54HG004028 · NHGRI · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2005 to 2014
$36.2M
Collaborative Development of Biomedical Ontologies and TerminologiesR01GM086587 · NIGMS · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2009 to 2016
$4.1M
Protege: A Knowledge-Engineering Environment for Advancing Biomedical SciencesR01GM121724 · NIGMS · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2017 to 2020
$2.3M
Protege: An Ontology-Development Platform for Biomedical ScientistsR01GM103316 · NIGMS · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2013 to 2016
$2.1M
NHGRI NIH HHS U54 HG004028NIGMS NIH HHS R01 GM086587NIGMS NIH HHS R01 GM103316NIGMS NIH HHS R01 GM121724
6 · The paper itself

Abstract

While the biomedical community has published several "open data" sources in the last decade, most researchers still endure severe logistical and technical challenges to discover, query, and integrate heterogeneous data and knowledge from multiple sources. To tackle these challenges, the community has experimented with Semantic Web and linked data technologies to create the Life Sciences Linked Open Data (LSLOD) cloud. In this paper, we extract schemas from more than 80 biomedical linked open data sources into an LSLOD schema graph and conduct an empirical meta-analysis to evaluate the extent of semantic heterogeneity across the LSLOD cloud. We observe that several LSLOD sources exist as stand-alone data sources that are not inter-linked with other sources, use unpublished schemas with minimal reuse or mappings, and have elements that are not useful for data integration from a biomedical perspective. We envision that the LSLOD schema graph and the findings from this research will aid researchers who wish to query and integrate data and knowledge from multiple biomedical sources simultaneously on the Web.

Indexed as

Biological Science DisciplinesInformation Storage and RetrievalAnimalsHumansMeta-Analysis as TopicSemantics

Identifiers

PMID33479214
PMCPMC7819992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.