Evidence map›Paper›PMID 33479200›Full record

ArticleCell death & disease2021

Tubular Mas receptor mediates lipid-induced kidney injury.

Yonglun Kong, Xiaoduo Zhao, Miaojuan Qiu, Yu Lin, Pinning Feng, Suchun Li, Baien Liang, Qing Zhu, Hui Huang, Chunling Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Role of G protein coupled receptors in acute kidney injury.Cell communication and signaling : CCS · 2024
    Review
  5. Article
  6. Article
  7. Review
  8. Autophagy and regulation of aquaporins in the kidneys.Kidney research and clinical practice · 2023
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yonglun KongDepartment of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
Xiaoduo ZhaoDepartment of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
Miaojuan QiuDepartment of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
Yu LinDepartment of Pathology, Zhujiang Hospitial, Southern Medical University, Guangzhou, 510282, China.
Pinning FengDepartment of Clinical Laboratory, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Suchun LiDepartment of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
Baien LiangDepartment of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
Qing ZhuGuangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine, Guangdong Pharmaceutical University, Guangzhou, 510006, China.
Hui HuangDepartment of Cardiology, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518033, China.
Chunling LiInstitute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China. lichl3@mail.sysu.edu.cn.
Weidong WangDepartment of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China. wangwd6@mail.sysu.edu.cn.ORCID 0000-0003-2523-3145
Sun Yat-sen University · CNGuangdong Pharmaceutical University · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity-related kidney diseases are becoming serious health problems worldwide, yet the mechanism by which obesity causes kidney injury is not fully understood. The purpose of current study was to investigate the role of Mas receptor in lipid-induced kidney injury. In mice fed with high-fat diet (HFD), the protein abundance of markers of autophagy, endoplasmic reticulum stress (ER stress) and apoptosis was dramatically increased in the kidney cortex, which was markedly prevented by Mas deletion (Mas

Indexed as

Angiotensin IIAnimalsAutophagyCell LineDiet, High-FatEndoplasmic Reticulum StressHumansKidney DiseasesKidney Tubules, ProximalMaleMiceMice, Inbred C57BLObesityPeptide FragmentsProto-Oncogene MasProto-Oncogene Proteins7-Ala-angiotensin (1-7)Angiotensin IIPeptide FragmentsProto-Oncogene MasProto-Oncogene ProteinsReceptors, G-Protein-Coupled

Identifiers

PMID33479200
PMCPMC7817966
OpenAlexW3124393267

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.