ArticleClinical medicine (London, England)2021
Medically unexplained symptoms: assessment and management.
Article in Clinical medicine (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Prevalence of Associated Extraoral Symptoms and Comorbidities in Burning Mouth Syndrome Patients: A Systematic Review.Oral diseases · 2026Pooled it
- Monitoring and evaluation instruments of individual health in community settings: a scoping review.Archives of public health = Archives belges de sante publique · 2026Pooled it
- Clinical skills development for healthcare practitioners working with patients with persistent physical symptoms (PPS) in healthcare settings: a systematic review and narrative synthesis.BMC medical education · 2024Pooled it
- Safety and efficacy of Ninjin'yoeito along with iron supplementation therapy for preoperative anemia, fatigue, and anxiety in patients with gynecological disease: an open-label, single-center, randomized phase-II trial.BMC women's health · 2022Trial
- Diagnostic Anchoring on Positive Autoimmune Serologies in Polysymptomatic Patients.Journal of general internal medicine · 2026Article
- Identifying past-year self-reported suicidality in outpatients with somatic symptom disorder using an interpretable machine-learning model: a multicenter study with an online calculator.BMC psychiatry · 2026Observational
- Article
- The lived experience of long COVID: A thematic analysis of an in-depth interview study.PLOS mental health · 2026Article
- What deters GPs from talking about sexual assault? a qualitative interview study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Article
- The challenge of persistent physical symptoms.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Article
- Efficacy of cognitive and behavioral therapy (CBT) treatment for individuals living with symptoms associated with environmental factors (SAEF): protocol for a randomized controlled trial.BMC psychology · 2025Article
- The High-Risk Model of Threat Perception Modulates Learning of Placebo and Nocebo Effects and Functional Somatic Disorders.Brain sciences · 2025Review
- Psychological factors and obesity, not thyroid biomarkers, predict thyroid-dependent quality of life in treated hypothyroidism: a cross-sectional study.BMC endocrine disorders · 2025Article
- Unexplained breathlessness: Integrating pathophysiological insights with clinical evaluation.Clinical medicine (London, England) · 2025Review
- Associations of fluctuations in blood glucose and insulin with hypoglycemic symptoms.Scientific reports · 2025Article
- Extent of Unidentified Complaints and Depression Is Inversely Associated with Fish and Shellfish Intake in Young Japanese Women.Nutrients · 2025Article
- Case Report: The intersection of psychiatry and medicine: diagnostic and ethical insights from case studies.Frontiers in psychiatry · 2025Article
- The role of sensory attenuation in symptomatic and healthy individuals: a scoping review.Frontiers in neuroscience · 2025Review
- A DNA2 mutation in the ATP-binding motif identified in a diagnostically unresolved individual.Frontiers in molecular biosciences · 2025Article
- Introducing a new specifier for functional somatic disorder: a psychodynamic approach to investigating emotional factors.Frontiers in psychiatry · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Medically unexplained symptoms or persistent physical symptoms are common, real and are associated with significant distress, loss of functioning and high healthcare costs. History, examination and appropriate investigations are essential to make a diagnosis. Once the diagnosis has been made, exploring the impact of the symptoms helps us to tailor our advice to patients. This paper sets out a practical approach to taking a history, assessment and stepwise management principles.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.