Evidence map›Paper›PMID 33478956›Full record

ArticleArchives of disease in childhood. Fetal and neonatal edition2021

Associations between family presence and neonatal intubation outcomes: a report from the National Emergency Airway Registry for Neonates: NEAR4NEOS.

Brianna K Brei, Taylor Sawyer, Rachel Umoren, Megan M Gray, Jeanne Krick, Elizabeth E Foglia, Anne Ades, Kristen Glass, Jae H Kim, Neetu Singh and 13 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Archives of disease in childhood. Fetal and neonatal edition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Comparison of Unplanned Extubations Associated with Orotracheal versus Nasotracheal Intubation in Infants.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 15 institutions in 5 countries.

Brianna K BreiPediatrics, Division of Neonatology, University of Nebraska Medical Center, Omaha, Nebraska, USA brianna.brei@unmc.edu.ORCID http://orcid.org/0000-0003-0481-3597
Taylor SawyerPediatrics, Division of Neonatology, University of Washington School of Medicine, Seattle, Washington, USA.
Rachel UmorenPediatrics, Division of Neonatology, University of Washington School of Medicine, Seattle, Washington, USA.
Megan M GrayPediatrics, Division of Neonatology, University of Washington School of Medicine, Seattle, Washington, USA.ORCID http://orcid.org/0000-0002-3272-9432
Jeanne KrickDepartment of Pediatrics, Madigan Army Medical Center, Tacoma, Washington, USA.
Elizabeth E FogliaDepartment of Pediatrics, Division of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID http://orcid.org/0000-0002-9925-5219
Anne AdesDepartment of Pediatrics, Division of Neonatology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Kristen GlassDepartment of Pediatrics, Division of Neonatology, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA.
Jae H KimPerinatal Institute, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Neetu SinghNeonatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Philipp JungPediatrics, Universitatsklinikum Schleswig-Holstein, Kiel, Schleswig-Holstein, Germany.
Lindsay JohnstonDepartment of Pediatrics, Yale School of Medicine, New Haven, Connecticut, USA.
Ahmed MoussaPediatrics- Neonatology, Centre Hospitalier Universitaire Sainte-Justine, Montreal, Québec, Canada.ORCID http://orcid.org/0000-0002-2556-6970
Natalie NapolitanoNursing and Respiratory Care, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
James BarryPediatrics, Section of Neonatology, University of Colorado Denver School of Medicine, Aurora, Colorado, USA.
Jeanne ZengePediatrics, Section of Neonatology, University of Colorado Denver School of Medicine, Aurora, Colorado, USA.
Binhuey QuekDepartment of Neonatology, KK Women's and Children's Hospital, Singapore.
Stephen D DeMeoPediatrics, WakeMed Health and Hospitals, Raleigh, North Carolina, USA.
Justine ShultsEpidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Jennifer UnrauPediatrics, Section of Neonatology, University of Calgary Cumming School of Medicine, Calgary, Alberta, Canada.
Vinay NadkarniAnesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Akira NishisakiAnesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
National Emergency Airway Registry for Neonates (NEAR4NEOS) investigators
Children's Hospital of Philadelphia · USUniversity of Washington · USPediatrics and Genetics · USCancer Research And Biostatistics · USCentre Hospitalier Universitaire Sainte-Justine · CACincinnati Children's Hospital Medical Center · USDartmouth–Hitchcock Medical Center · USKK Women's and Children's Hospital · SGMadigan Army Medical Center · USNebraska Medical Center · USPenn State Milton S. Hershey Medical Center · USUniversity Hospital Schleswig-Holstein · DEUniversity of Calgary · CAWakeMed · USYale University · US

Funding

Patient Safety Learning Laboratory to Enhance the Value and Safety of Neonatal Interfacility Transfers in a Regional Care NetworkR18HS027259 · AHRQ · UNIVERSITY OF WASHINGTON · PI UMOREN, RACHEL A · 2019 to 2022
$2.4M
Improving the Safety of Pediatric Tracheal Intubations in ICUs with Apneic Oxygenation and Video LaryngoscopesR18HS024511 · AHRQ · CHILDREN'S HOSP OF PHILADELPHIA · PI NISHISAKI, AKIRA · 2016 to 2019
$996k
Optimizing Respiratory Function in Delivery Room Resuscitation: The INFLATE Study (INFant Lung Aeration during Transition Events)K23HD084727 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI FOGLIA, ELIZABETH · 2016 to 2020
$809k
Improving safety and quality of tracheal intubations in neonatal ICUsR21HD089151 · NICHD · CHILDREN'S HOSP OF PHILADELPHIA · PI NISHISAKI, AKIRA · 2017 to 2018
$470k
Next Generation Integrated Curriculum and Trainer for Neonate ResuscitationR21HD091687 · NICHD · UNIVERSITY OF WASHINGTON · PI SAWYER, TAYLOR L, SWEET, ROBERT MARTEN · 2018 to 2019
$415k
AHRQ HHS R18 HS024511AHRQ HHS R18 HS027259NICHD NIH HHS K23 HD084727NICHD NIH HHS R21 HD089151NICHD NIH HHS R21 HD091687
6 · The paper itself

Abstract

objectiveDescribe the current practice of family presence during neonatal tracheal intubations (TIs) across neonatal intensive care units (NICUs) and examine the association with outcomes.

designRetrospective analysis of TIs performed in NICUs participating in the National Emergency Airway Registry for Neonates (NEAR4NEOS).

settingThirteen academic NICUs. PATIENTS: Infants undergoing TI between October 2014 and December 2017.

main outcome measuresAssociation of family presence with TI processes and outcomes including first attempt success (primary outcome), success within two attempts, adverse TI-associated events (TIAEs) and severe oxygen desaturation ≥20% from baseline.

resultsOf the 2570 TIs, 242 (9.4%) had family presence, which varied by site (median 3.6%, range 0%-33%; p<0.01). Family member was more often present for older infants and those with chronic respiratory failure. Fewer TIs were performed by residents when family was present (FP 10% vs no FP 18%, p=0.041). Among TIs with family presence versus without family presence, the first attempt success rate was 55% vs 49% (p=0.062), success within two attempts was 74% vs 66% (p=0.014), adverse TIAEs were 18% vs 20% (p=0.62) and severe oxygen desaturation was 49% vs 52%, (p=0.40). In multivariate analyses, there was no independent association between family presence and intubation success, adverse TIAEs or severe oxygen desaturation.

conclusionFamily are present in less than 10% of TIs, with variation across NICUs. Even after controlling for important patient, provider and site factors, there were no significant associations between family presence and intubation success, adverse TIAEs or severe oxygen desaturation.

Indexed as

Academic Medical CentersFamilyFemaleGestational AgeHumansInfantInfant, NewbornIntensive Care Units, NeonatalIntubation, IntratrachealMaleOximetryOxygenProspective StudiesRegistriesRetrospective StudiesOxygenhealth services researchneonatology

Identifiers

PMID33478956
PMCPMC8237190
OpenAlexW3121982746

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.