Evidence map›Paper›PMID 33478917›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2021

A Co-Twin Control Study of the Association Between Bullying Victimization and Self-Harm and Suicide Attempt in Adolescence.

Lauren M O'Reilly, Erik Pettersson, Patrick D Quinn, E David Klonsky, Jessie R Baldwin, Sebastian Lundström, Henrik Larsson, Paul Lichtenstein, Brian M D'Onofrio

Open access · greenAbstract readTwin Study
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Lauren M O'ReillyDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana. Electronic address: loreilly@iu.edu.
Erik PetterssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Patrick D QuinnDepartment of Applied Health Statistics, School of Public Health, Indiana University, Bloomington, Indiana.
E David KlonskyDepartment of Psychology, University of British Columbia, Vancouver, British Colombia, Canada.
Jessie R BaldwinDivision of Psychology and Language Sciences, Department of Clinical, Educational and Health Psychology, University College London, London, UK; Social Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Sebastian LundströmDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Göteborg, Sweden.
Henrik LarssonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; School of Medical Sciences, Örebro University, Örebro, Sweden.
Paul LichtensteinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Brian M D'OnofrioDepartment of Psychological and Brain Sciences, Indiana University, Bloomington, Indiana; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Karolinska Institutet · SEIndiana University Bloomington · USKing's College London · GBÖrebro University · SEUniversity of British Columbia · CAUniversity of Gothenburg · SE

Funding

Pharmacoepidemiologic Studies of Prescription Opioid Analgesic RisksR00DA040727 · NIDA · TRUSTEES OF INDIANA UNIVERSITY · PI QUINN, PATRICK DONOVAN · 2018 to 2020
$744k
Predicting Short-Term Risk for Suicidal Behavior after Contact with Outpatient Specialists: A Machine Learning ApproachF31MH121039 · NIMH · TRUSTEES OF INDIANA UNIVERSITY · PI O'REILLY, LAUREN MARIE · 2019 to 2021
$139k
NIDA NIH HHS R00 DA040727NIMH NIH HHS F31 MH121039Wellcome Trust
6 · The paper itself

Abstract

purposeThe aim of the study was to investigate the magnitude of an independent association between bullying victimization and self-harm and suicide attempt in adolescence after adjusting for unmeasured and measured confounding factors.

methodsUsing the Child and Adolescent Twin Study in Sweden, we examined twins born between 1994 and 1999 (n = 13,852). Twins self-reported bullying victimization at age 15 years and self-harm and suicide attempt at age 18 years. We created a factor score of 13 bullying items, on which self-harm and suicide attempt items were regressed in three models: (1) among unrelated individuals; (2) among co-twins, in which a twin exposed to more bullying was compared with his/her co-twin who was exposed to less; and (3) among co-twins while adjusting for indicators of childhood psychopathology.

resultsAmong unrelated individuals, a one standard deviation increase in bullying victimization was associated with increased odds for self-harm (odds ratio [OR], 1.29 [95% confidence interval, 1.23-1.36]) and suicide attempt (OR, 1.68 [1.53-1.85]). Among co-twins, the odds attenuated for self-harm (OR, 1.19 [1.09-1.30]) and suicide attempt (OR, 1.39 [1.17-1.66]). Finally, when accounting for childhood psychopathology, there was a 14% (1.04-1.25) and 25% (1.03-1.52) relative increase in odds of self-harm and suicide attempt, respectively.

conclusionsThe results suggest that bullying victimization was uniquely associated with self-harm and suicide attempt over and above the confounding because of unmeasured and measured factors (i.e., familial vulnerability and pre-existing psychopathy). However, magnitudes were small, suggesting that additional interventions and screenings are needed to address suicidality apart from bullying interventions.

Indexed as

BullyingCrime VictimsSelf-Injurious BehaviorAdolescentFemaleHumansMaleSuicide, AttemptedSwedenBullying victimizationCo-twinSelf-harmSuicide attempt

Identifiers

PMID33478917
PMCPMC8286262
OpenAlexW3122411234

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.