Evidence map›Paper›PMID 33478744›Full record

ArticleTransplantation proceedings2021

Restarting LDLT During COVID-19: Early Results After Restructuring.

Sandeep K Jha, Imtiakum Jamir, Kshitij Sisodia, Niteen Kumar, Gaurav Sood, Nitin Shanker, Sachin Anand, Gaurav Dubey, Vinod Choudhary, Pankaj Lohia and 4 more

Open access · greenAbstract read
In one paragraph

Article in Transplantation proceedings, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Living Donor Liver Transplantation During the COVID-19 Pandemic: an Evolving Challenge.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Sandeep K JhaDepartment of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India. Electronic address: drskjha@live.com.
Imtiakum JamirDepartment of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
Kshitij SisodiaDepartment of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
Niteen KumarDepartment of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
Gaurav SoodDepartment of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
Nitin ShankerDepartment of Liver Transplant Critical Care, BL Kapur Superspeciality Hospital, Delhi, India.
Sachin AnandDepartment of Liver Transplant Critical Care, BL Kapur Superspeciality Hospital, Delhi, India.
Gaurav DubeyDepartment of Liver Transplant & HPB Anaesthesia, BL Kapur Superspeciality Hospital, Delhi, India.
Vinod ChoudharyDepartment of Liver Transplant & HPB Anaesthesia, BL Kapur Superspeciality Hospital, Delhi, India.
Pankaj LohiaDepartment of Liver Transplant Critical Care, BL Kapur Superspeciality Hospital, Delhi, India.
Amit SinghalDepartment of Liver Transplant & HPB Anaesthesia, BL Kapur Superspeciality Hospital, Delhi, India.
Manav WadhawanInstitute of Digestive and Liver Diseases, BL Kapur Superspeciality Hospital, Delhi, India.
Ajay KumarInstitute of Digestive and Liver Diseases, BL Kapur Superspeciality Hospital, Delhi, India.
Abhideep ChaudharyDepartment of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
BLK Super Speciality Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionLiving-donor liver transplantation (LDLT) has been mostly suspended and deceased-donor living transplantation activity has been considerably reduced because of coronavirus disease 2019 (COVID-19). We modified our protocols and procedures in line with COVID-19 guidelines. Since the restructuring, we have performed 20 LDLTs. Our study reports the outcomes of these cases and demonstrates the feasibility of LDLT during this pandemic. MATERIALS AND

methodsThe changes were influenced by experiences and communications from across the globe. A month-long self-imposed moratorium was spent in restructuring the program and implementing new protocols. Twenty LDLTs were performed between April 18 and September 15 using the new protocols. Our experience includes 2 simultaneous liver-kidney transplants, 1 ABO-incompatible LDLT, and 1 pediatric case (age 11 months).

resultsNineteen patients recovered and 1 patient died. We maintained our postoperative immunosuppression protocol without many changes. Major complications were observed in 30% of recipients but none of the donors. One recipient was infected with COVID-19 during the postoperative period. A donor-recipient couple contracted COVID-19 after discharge from the hospital. All patients recovered from COVID-19 and liver enzymes were unaffected.

conclusionThis study represents a microcosm of experience in LDLT during the COVID-19 era. Outcomes of LDLT are not affected by COVID-19 per se, provided that we make necessary changes.

Indexed as

SARS-CoV-2ABO Blood-Group SystemAdultBlood Group IncompatibilityCOVID-19FemaleHumansImmunosuppression TherapyInfantInfection ControlLiver TransplantationLiving DonorsMaleMiddle AgedPostoperative ComplicationsPostoperative PeriodABO Blood-Group System

Identifiers

PMID33478744
PMCPMC7836215
OpenAlexW3112463886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.