ArticleMicrobiome2021
Decoding the RNA viromes in rodent lungs provides new insight into the origin and evolutionary patterns of rodent-borne pathogens in Mainland Southeast Asia.
Article in Microbiome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.
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Who cites it
67 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.
- Diversity and transmission and zoonotic potential of microbes in true insectivores.Nature communications · 2025Pooled it
- Viral metagenomics of synanthropic urban bats: A surveillance strategy for uncovering potentially zoonotic viruses.One health (Amsterdam, Netherlands) · 2026Article
- Global status, bias risks, and ecological integration of wild bat and rodent virome research.One health (Amsterdam, Netherlands) · 2026Review
- RNA Virus Diversity, Cross-Species Transmission, and Molecular Constraints in Two Closely Related Rat Species.Integrative zoology · 2026Article
- Rattus norvegicus and Rattus tanezumi as hub hosts for viral diversity and potential spillover on Hainan Island, China.NPJ biofilms and microbiomes · 2026Article
- Molecular prevalence, genomic characterization, and zoonotic potential of novel paramyxovirus and hepacivirus in Alexandromys fortis, Republic of Korea.Veterinary research · 2026Article
- A global-scale assessment of zoonotic virus diversity and spillover potential in urban-adapted mammal species.Nature microbiology · 2026Article
- Characteristics of RNA viruses in rodents across different ecological regions of Yunnan and analysis of their evolutionary patterns and replication potential.BMC microbiology · 2026Article
- Detection of Wencheng shrew virus and cardiovirus from small mammals in Myanmar.Scientific reports · 2026Article
- Zoological transmission of encephalomyocarditis virus in the United States: Virus evolution, host ecology, and capsid antigenicity derived from an outbreak.PLoS pathogens · 2026Article
- Highly divergent virome in wild rodents of Xinjiang, China: Implications for rodent origin of porcine reproductive and respiratory syndrome virus 1.Zoological research · 2026Article
- Burden of rodent-borne viruses in rodents and zoonotic risk in humans in Cambodia.Microbiology spectrum · 2026Article
- Whole-Genome Characterization of Rodent Coronaviruses (RCoVs) in Thailand, 2024-2025.Transboundary and emerging diseases · 2026Article
- Unveiling the RNA viral diversity in three organs of the Asian house shrew (Frontiers in microbiology · 2026Article
- Infectome analysis of small mammals in Southern China reveals pathogen ecology and emerging risks.Nature communications · 2025Article
- Metagenomic Sequencing Reveals the Viral Diversity of Bactrian Camels in China.Microorganisms · 2025Article
- In vivo and in vitro recombinant systems of a novel variant demonstrate cross-reactive neutralization for the HCV model virus, Norway rat hepacivirus.PLoS pathogens · 2025Article
- Mapping the Potential Risk of Coronavirus Spillovers in a Global Hotspot.Global change biology · 2025Article
- Virome diversity in small mammals from south China: Insights into virus evolution, transmission, and ecology.Virologica Sinica · 2025Article
- Coronaviruses in wild rodent and eulipotyphlan small mammals: a review of diversity, ecological implications and surveillance considerations.The Journal of general virology · 2025Review
7 more citing papers are in PubMed but not listed here.
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Authors and funding
28 authors at 8 institutions in 6 countries.
Funding
Abstract
backgroundAs the largest group of mammalian species, which are also widely distributed all over the world, rodents are the natural reservoirs for many diverse zoonotic viruses. A comprehensive understanding of the core virome of diverse rodents should therefore assist in efforts to reduce the risk of future emergence or re-emergence of rodent-borne zoonotic pathogens.
resultsThis study aimed to describe the viral range that could be detected in the lungs of rodents from Mainland Southeast Asia. Lung samples were collected from 3284 rodents and insectivores of the orders Rodentia, Scandentia, and Eulipotyphla in eighteen provinces of Thailand, Lao PDR, and Cambodia throughout 2006-2018. Meta-transcriptomic analysis was used to outline the unique spectral characteristics of the mammalian viruses within these lungs and the ecological and genetic imprints of the novel viruses. Many mammalian- or arthropod-related viruses from distinct evolutionary lineages were reported for the first time in these species, and viruses related to known pathogens were characterized for their genomic and evolutionary characteristics, host species, and locations.
conclusionsThese results expand our understanding of the core viromes of rodents and insectivores from Mainland Southeast Asia and suggest that a high diversity of viruses remains to be found in rodent species of this area. These findings, combined with our previous virome data from China, increase our knowledge of the viral community in wildlife and arthropod vectors in emerging disease hotspots of East and Southeast Asia. Video abstract.
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