Evidence map›Paper›PMID 33478469›Full record

ArticleBMC public health2021

Suubi+Adherence-Round 2: A study protocol to examine the longitudinal HIV treatment adherence among youth living with HIV transitioning into young adulthood in Southern Uganda.

Fred M Ssewamala, Ozge Sensoy Bahar, Proscovia Nabunya, April D Thames, Torsten B Neilands, Christopher Damulira, Barbara Mukasa, Rachel Brathwaite, Claude Mellins, John Santelli and 6 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01790373 (Suubi+Adherence), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01790373 naactive not recruitingnot on this map

Suubi+Adherence: Evaluating a Youth-Focused Economic Empowerment Approach to HIV Treatment Adherence

TypeinterventionalSponsorWashington University School of MedicineRan2013 to 2026Enrolled702ConditionsHIVArmsSuubi+Adherence, Bolstered Standard of Care
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 2 countries.

Fred M SsewamalaBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA. fms1@wustl.edu.
Ozge Sensoy BaharBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA.
Proscovia NabunyaBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA.
April D ThamesDepartment of Psychology, University of Southern California, 3620 S. McClintock Avenue Rm 520, Los Angeles, CA, 90089, USA.
Torsten B NeilandsSchool of Medicine, University of California San Francisco, 550 16th Street, San Francisco, CA, 94158, USA.
Christopher DamuliraBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA.
Barbara MukasaMildmay Uganda, 12 Km Entebbe Road, Naziba Hill, Lweza, Kampala, Uganda.
Rachel BrathwaiteBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA.
Claude MellinsHIV Center for Clinical & Behavioral Studies, New York State Psychiatric Institute and Columbia University, 1051 Riverside Dr, New York, NY, 10032, USA.
John SantelliDepartment of Population and Family Health, Columbia University Mailman School of Public Health, 60 Haven Ave B-4 Suite 432, New York, NY, 10032, USA.
Derek BrownBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA.
Shenyang GuoBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA.
Phionah NamatovuBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA.
Joshua KiyingiBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA.
Flavia NamuwongeInternational Center for Child Health and Development Field Office, Plot 23 Circular Rd, Masaka, Uganda.
Mary M McKayBrown School, Washington University in St. Louis, 1 Brookings Drive, St. Louis, MO, 63130, USA.
Washington University in St. Louis · USColumbia University · USMildmay Uganda · UGNew York Psychoanalytic Society and Institute · USUniversity of California, San Francisco · USUniversity of Southern California · US

Funding

Suubi+Adherence-R2: Examining the longitudinal HIV treatment adherence among youth living with HIV (YLHIV) transitioning into young adulthoodR01HD074949 · NICHD · WASHINGTON UNIVERSITY · PI NABUNYA, PROSCOVIA, SENSOY BAHAR, OZGE · 2012 to 2024
$7.7M
National Survey of State Policy Decision-making and SimulationP50MH113662 · NIMH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HOAGWOOD, KIMBERLY E. · 2019 to 2022
$6.9M
Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
Strengthening Child Health Research Capacity in Resource Constrained Settings: Researcher Resilience Training (RRT)R25MH118935 · NIMH · WASHINGTON UNIVERSITY · PI SEAN JOE, Mary McKernan McKay · 2018 to 2026
$1.5M
NICHD NIH HHS R01 HD074949NIMH NIH HHS P50 MH113662NIMH NIH HHS R25 MH067127NIMH NIH HHS R25 MH118935
6 · The paper itself

Abstract

backgroundYouth living with HIV (YLHIV) in Sub-Saharan African (SSA) are less likely to adhere to antiretroviral therapy (ART) and other health-related regimens. As a consequence, YLHIV are not only at risk for health problems and mental health comorbidities, but are also at risk for cognitive deficits, including in areas of memory and executive functioning. The Suubi+Adherence study followed 702 adolescents (10-16 years of age) receiving bolstered standard of care and a family economic empowerment intervention comprising an incentivized youth financial savings account (YSA) augmented with financial literacy training (FLT) and peer mentorship. The study findings pointed to superior short-term viral suppression and positive adolescent health and mental health functioning among participants receiving the intervention. The original group of adolescents who received Suubi+Adherence are now transitioning into young adulthood. This paper presents a protocol for the follow-up phase titled Suubi+Adherence Round 2.

methodsThe original cohort in Suubi+Adherence will be tracked for an additional five years (2020-2025). Specifically, the long term follow-up will allow to: 1) ascertain the extent to which the short term outcomes identified in the first 6 years of the intervention are maintained as the same group transitions through young adulthood; and 2) address new scientific questions regarding ART adherence; HIV care engagement; protective health behaviors; and the potential of FEE to mitigate the development of HIV-associated neurocognitive disorders in YLHIV. Additionally, the team examines the potential mechanisms through which the observed long-term outcomes happen. Moreover, the Suubi+Adherence-Round 2 adds a qualitative component and extends the cost effectiveness component. DISCUSSION: Guided by asset and human development theories, Suubi+Adherence-R2 will build on the recently concluded Suubi+Adherence study to conduct one of the largest and longest running studies of YLHIV in SSA as they transition into young adulthood. The study will address new scientific questions regarding long-term ART adherence, HIV care engagement, protective health behaviors, and the potential of FEE to mitigate the development of HIV-associated neurocognitive disorders in YLHIV. The findings may inform efforts to improve HIV care among Uganda's YLHIV, with potential replicability in other low-resource countries.

trial registrationClinicalTrials.gov , ID: NCT01790373.

Indexed as

HIV InfectionsAdolescentAdolescent HealthAdultHumansMedication AdherenceTreatment Adherence and ComplianceUgandaYoung Adultcohorteconomic empowermentHIV/AIDSsub-Saharan AfricaUgandaYouth living with HIV

Identifiers

PMID33478469
PMCPMC7818782
OpenAlexW3124435633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.