Evidence map›Paper›PMID 33478430›Full record

ArticleBMC infectious diseases2021

Point-prevalence survey of outpatient antibiotic prescription at a tertiary medical center in Sri Lanka: opportunities to improve prescribing practices for respiratory illnesses.

Helen L Zhang, Champica Bodinayake, Gaya B Wijayaratne, Pasangi Jayatissa, D L Bhagya Piyasiri, Ruvini Kurukulasooriya, Tianchen Sheng, Ajith Nagahawatte, Christopher Woods, L Gayani Tillekeratne

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Antibiotics Use Patterns in Low- and Middle-Income Countries: A Systematic Review Analysis.Inquiry : a journal of medical care organization, provision and financing
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Helen L ZhangDivision of Infectious Diseases, University of Pennsylvania Health System, Philadelphia, PA, USA. helen.zhang1@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0001-8978-1832
Champica BodinayakeFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Gaya B WijayaratneFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Pasangi JayatissaFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
D L Bhagya PiyasiriTeaching Hospital Karapitiya, Galle, Sri Lanka.
Ruvini KurukulasooriyaFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Tianchen ShengDuke Global Health Institute, Duke University, Durham, NC, USA.
Ajith NagahawatteFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
Christopher WoodsDuke Global Health Institute, Duke University, Durham, NC, USA.
L Gayani TillekeratneFaculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
University of Ruhuna · LKDuke University · USTeaching Hospital Kandy · LKUniversity of Pennsylvania Health System · US

Funding

Novel Diagnostics to Improve Antimicrobial Stewardship for Acute Respiratory Tract Infections in Resource-Limited SettingsK23AI125677 · NIAID · DUKE UNIVERSITY · PI TILLEKERATNE, GAYANI · 2017 to 2021
$905k
National Institute of Allergy and Infectious Diseases K23AI125677NIAID NIH HHS K23 AI125677
6 · The paper itself

Abstract

backgroundInappropriate antibiotic use is linked to the spread of antimicrobial resistance worldwide, but there are limited systemic data on antibiotic utilization in low- and middle-income countries. The purpose of this study was to evaluate the prevalence and patterns of antibiotic prescription in an ambulatory care setting in Sri Lanka.

methodsThis cross-sectional survey was conducted at the Outpatient Department of a public tertiary medical center in Southern Province, Sri Lanka from February to April 2019. Among consecutive outpatients presenting for care, questionnaires were verbally administered to a systematic random sample to capture information about patient demographics, illness characteristics, and visit outcomes. Prescription data were obtained from the outpatient pharmacy's electronic prescribing system.

resultsOf 409 surveyed patients, 146 (35.7%) were prescribed an antibiotic. The most frequently prescribed agents were amoxicillin (41 patients, 28.1% of antibiotic recipients) and first-generation cephalosporins (38, 26.0%). Respiratory indications were the most common reason for antibiotic use, comprising 69 (47.3%) of all antibiotic prescriptions. Antibiotics were prescribed for 66.1% of patients presenting with cough and 78.8% of those presenting with rhinorrhea or nasal congestion. Among all antibiotic recipients, 6 (4.1%) underwent diagnostic studies.

conclusionsA high prevalence of antibiotic prescription was observed, in particular for treatment of respiratory conditions. These data support the need for improved antimicrobial stewardship in the Sri Lankan outpatient setting.

Indexed as

AdolescentAdultAmbulatory CareAnti-Bacterial AgentsAntimicrobial StewardshipChildCross-Sectional StudiesFemaleHealth Care SurveysHumansMaleMiddle AgedOutpatientsPractice Patterns, Physicians'PrescriptionsPrevalenceAnti-Bacterial AgentsAntibiotic stewardshipAntibiotic useOutpatientsRespiratory tract infectionsSri Lanka

Identifiers

PMID33478430
PMCPMC7818802
OpenAlexW3124688071

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.