ArticleBMC genomics2021
Regulation of the antennal transcriptome of the dengue vector, Aedes aegypti, during the first gonotrophic cycle.
Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 45 citations in OpenAlex.
- Two neuropeptides that promote blood feeding ineLife · 2026Article
- Age-dependent perception of floral emissions and the role of COScientific reports · 2026Article
- Diurnal fluctuating temperature and larval resource level interact to influence the life history and behaviour of disease-transmitting mosquitoes.Parasites & vectors · 2026Article
- Impact of elevated COScientific reports · 2025Article
- Article
- Odorant receptors for floral- and plant-derived volatiles in the yellow fever mosquito, Aedes aegypti (Diptera: Culicidae).PloS one · 2024Article
- Knockout of OR39 reveals redundancy in the olfactory pathway regulating the acquisition of host seeking inProceedings. Biological sciences · 2023Article
- Genetic mechanisms modulating behaviour through plastic chemosensory responses in insects.Molecular ecology · 2023Review
- The antennal transcriptome of Triatoma infestans reveals substantial expression changes triggered by a blood meal.BMC genomics · 2022Article
- Chemosensory ionotropic receptors in human host-seeking mosquitoes.Current opinion in insect science · 2022Review
- Identification of stage-related and severity-related biomarkers and exploration of immune landscape for Dengue by comprehensive analyses.Virology journal · 2022Article
- Deletion of the Serotonin Receptor 7 Gene Changed the Development and Behavior of the Mosquito,Insects · 2022Article
- Odorant-receptor-mediated regulation of chemosensory gene expression in the malaria mosquito Anopheles gambiae.Cell reports · 2022Article
- Modulation of odour-guided behaviour in mosquitoes.Cell and tissue research · 2021Review
- Olfaction-Related Gene Expression in the Antennae of Female Mosquitoes From CommonFrontiers in physiology · 2021Article
- Olfaction in Anopheles mosquitoes.Chemical senses · 2021Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the light of dengue being the fastest growing transmissible disease, there is a dire need to identify the mechanisms regulating the behaviour of the main vector Aedes aegypti. Disease transmission requires the female mosquito to acquire the pathogen from a blood meal during one gonotrophic cycle, and to pass it on in the next, and the capacity of the vector to maintain the disease relies on a sustained mosquito population.
resultsUsing a comprehensive transcriptomic approach, we provide insight into the regulation of the odour-mediated host- and oviposition-seeking behaviours throughout the first gonotrophic cycle. We provide clear evidence that the age and state of the female affects antennal transcription differentially. Notably, the temporal- and state-dependent patterns of differential transcript abundance of chemosensory and neuromodulatory genes extends across families, and appears to be linked to concerted differential modulation by subsets of transcription factors.
conclusionsBy identifying these regulatory pathways, we provide a substrate for future studies targeting subsets of genes across disparate families involved in generating key vector behaviours, with the goal to develop novel vector control tools.
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