Evidence map›Paper›PMID 33478134›Full record

ArticlePlants (Basel, Switzerland)2021

Cytotoxicity of Ficus Crocata Extract on Cervical Cancer Cells and Protective Effect against Hydrogen Peroxide-Induced Oxidative Stress in HaCaT Non-Tumor Cells.

Brenda De la Cruz-Concepción, Mónica Espinoza-Rojo, Patricia Álvarez-Fitz, Berenice Illades-Aguiar, Macdiel Acevedo-Quiroz, Ana E Zacapala-Gómez, Napoleón Navarro-Tito, Hilda Jiménez-Wences, Francisco I Torres-Rojas, Miguel A Mendoza-Catalán

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Kuwanon A fromAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Chemical Composition, Quality, and Bioactivity ofAntioxidants (Basel, Switzerland) · 2025
    Article
  3. Heliyon · 2022
    Article
  4. Frontiers in bioengineering and biotechnology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Brenda De la Cruz-ConcepciónLaboratorio de Biomedicina Molecular, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo 39090, Guerrero, Mexico.
Mónica Espinoza-RojoLaboratorio de Biología Molecular y Genómica, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo 39090, Guerrero, Mexico.ORCID 0000-0002-1854-2700
Patricia Álvarez-FitzLaboratorio de Toxicología, CONACYT-Universidad Autónoma de Guerrero, Chilpancingo 39090, Guerrero, Mexico.
Berenice Illades-AguiarLaboratorio de Biomedicina Molecular, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo 39090, Guerrero, Mexico.
Macdiel Acevedo-QuirozDepartamento de Química y Bioquímica, Tecnológico Nacional de México, Instituto Tecnológico/IT de Zacatepec, Calzada Tecnológico 27, Centro, Zacatepec 62780, Morelos, Mexico.
Ana E Zacapala-GómezLaboratorio de Biomedicina Molecular, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo 39090, Guerrero, Mexico.
Napoleón Navarro-TitoLaboratorio de Biología Celular del Cáncer, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo 39090, Guerrero, Mexico.ORCID 0000-0003-4911-0545
Hilda Jiménez-WencesLaboratorio de Investigación en Biomoléculas, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo 39090, Guerrero, Mexico.ORCID 0000-0003-1116-8733
Francisco I Torres-RojasLaboratorio de Biomedicina Molecular, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo 39090, Guerrero, Mexico.ORCID 0000-0003-4303-8677
Miguel A Mendoza-CatalánLaboratorio de Biomedicina Molecular, Facultad de Ciencias Químico-Biológicas, Universidad Autónoma de Guerrero, Chilpancingo 39090, Guerrero, Mexico.ORCID 0000-0002-6247-8590
Universidad Autónoma de Guerrero · MXTecnológico Nacional de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress causes several chronic diseases including cancer. Some chemotherapeutic agents are not selective against tumor cells, causing oxidative stress in non-tumor cells. This study aimed to evaluate the cytotoxic effect of acetone extract of

Indexed as

antioxidantsantitumor activitycervical cancercytoprotective effectFicus crocatahydrogen peroxideMoraceae

Identifiers

PMID33478134
PMCPMC7835743
OpenAlexW3124111336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.