Evidence map›Paper›PMID 33478112›Full record

ArticleInternational journal of environmental research and public health2021

Toothpastes with Enzymes Support Gum Health and Reduce Plaque Formation.

Pune N Paqué, Patrick R Schmidlin, Daniel B Wiedemeier, Florian J Wegehaupt, Phoebe D Burrer, Philipp Körner, Shengjile Deari, Michel-Angelo Sciotti, Thomas Attin

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Pune N PaquéClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.ORCID 0000-0002-4219-3395
Patrick R SchmidlinClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.ORCID 0000-0002-1377-0325
Daniel B WiedemeierStatistical Services, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.
Florian J WegehauptClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.ORCID 0000-0002-3972-0561
Phoebe D BurrerClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.
Philipp KörnerClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.
Shengjile DeariClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.
Michel-Angelo SciottiSchool of Life Sciences, Institute for Chemistry and Bioanalytics, University of Applied Sciences Northern Switzerland, Hofackerstrasse 30, 4132 Muttenz, Switzerland.
Thomas AttinClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.
University of Zurich · CHFHNW University of Applied Sciences and Arts · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Enzymes in toothpastes can support host immune responses, and thus maintain oral health. This study aimed to investigate gingival health and the plaque-reducing effects of enzyme-containing toothpastes. A laboratory study tested the antimicrobial potential of different enzyme-containing toothpaste formulations. Two promising formulations (enzyme-containing toothpastes with glucose oxidase and D-glucose with (C+) and without Citrox (C-) Citrox) were investigated in a clinical crossover trial (two slurries: sodium lauryl sulfate-containing (SLS), a toothpaste without SLS (reference), and water). Subjects (

Indexed as

GingivitisToothpastesDouble-Blind MethodGingivaHumansSodium Dodecyl SulfateToothbrushingSodium Dodecyl SulfateToothpastesbacteriadentifricegingivagingivitishigh responderlow responderpreventionprophylaxistoothbrushing

Identifiers

PMID33478112
PMCPMC7835853
OpenAlexW3123308572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.