ReviewBiosensors2021
The Ketogenic Diet: Breath Acetone Sensing Technology.
Review in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Is Breath Best? A Systematic Review on the Accuracy and Utility of Nanotechnology Based Breath Analysis of Ketones in Type 1 Diabetes.Biosensors · 2025Pooled it
- Use of an mHealth Ketogenic Diet App Intervention and User Behaviors Associated With Weight Loss in Adults With Overweight or Obesity: Secondary Analysis of a Randomized Clinical Trial.JMIR mHealth and uHealth · 2022Trial
- Article
- Review
- Article
- Optimizing metabolic health with digital twins.npj aging · 2025Review
- The role of β-hydroxybutyrate testing in ketogenic metabolic therapies.Frontiers in nutrition · 2025Review
- A solid state electrolyte based enzymatic acetone sensor.Scientific reports · 2024Article
- Innovations and applications of ketone body monitoring in diabetes care.Diabetology international · 2024Review
- Nanowire Array Breath Acetone Sensor for Diabetes Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Differences in Volatile Organic Compounds Between Concussed and Non-concussed Division I Athletes.Cureus · 2024Article
- Ultratrace eNose Sensing of VOCs toward Breath Analysis Applications Utilizing an eNose-Based Analyzer.ACS measurement science au · 2024Article
- A Novel Acetone Sensor for Body Fluids.Biosensors · 2023Article
- Continuous Monitoring of Interstitial Fluid Glucose Responses to Endurance Exercise with Different Levels of Carbohydrate Intake.Nutrients · 2023Article
- Efficacy of low carbohydrate and ketogenic diets in treating mood and anxiety disorders: systematic review and implications for clinical practice.BJPsych open · 2023Review
- A humidity-resistant and room temperature carbon soot@ZIF-67 composite sensor for acetone vapour detection.Nanoscale advances · 2023Article
- Non-Invasive Breath Analysis for Disease Screening and Diagnoses.Biosensors · 2022Article
- Commercial and Scientific Solutions for Blood Glucose Monitoring-A Review.Sensors (Basel, Switzerland) · 2022Review
- Adherence to Low-Carbohydrate Diets in Patients with Diabetes: A Narrative Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Review
- Harnessing Metabolomics to Advance Epilepsy Research.Epilepsy currentsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ketogenic diet, while originally thought to treat epilepsy in children, is now used for weight loss due to increasing evidence indicating that fat is burned more rapidly when there is a low carbohydrate intake. This low carbohydrate intake can lead to elevated ketone levels in the blood and breath. Breath and blood ketones can be measured to gauge the level of ketosis and allow for adjustment of the diet to meet the user's needs. Blood ketone levels have been historically used, but now breath acetone sensors are becoming more common due to less invasiveness and convenience. New technologies are being researched in the area of acetone sensors to capitalize on the rising popularity of the diet. Current breath acetone sensors come in the form of handheld breathalyzer devices. Technologies in development mostly consist of semiconductor metal oxides in different physio-chemical formations. These current devices and future technologies are investigated here with regard to utility and efficacy. Technologies currently in development do not have extensive testing of the selectivity of the sensors including the many compounds present in human breath. While some sensors have undergone human testing, the sample sizes are very small, and the testing was not extensive. Data regarding current devices is lacking and more research needs to be done to effectively evaluate current devices if they are to have a place as medical devices. Future technologies are very promising but are still in early development stages.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.