Evidence map›Paper›PMID 33478034›Full record

ArticleNutrients2021

Protective Effects of Medicinal Plant Decoctions on Macrophages in the Context of Atherosclerosis.

Eloïse Checkouri, Stéphane Ramin-Mangata, Nicolas Diotel, Wildriss Viranaicken, Claude Marodon, Franck Reignier, Christine Robert-Da Silva, Olivier Meilhac

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Aqueous Extract ofAntioxidants (Basel, Switzerland) · 2022
    Article
  4. The ethanol extract ofFrontiers in cardiovascular medicine · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Eloïse CheckouriUniversité de La Réunion, INSERM, UMR 1188 Diabète Athérothrombose Thérapies Réunion Océan Indien (DéTROI), 97490 Sainte-Clotilde, La Réunion, France.
Stéphane Ramin-MangataUniversité de La Réunion, INSERM, UMR 1188 Diabète Athérothrombose Thérapies Réunion Océan Indien (DéTROI), 97490 Sainte-Clotilde, La Réunion, France.
Nicolas DiotelUniversité de La Réunion, INSERM, UMR 1188 Diabète Athérothrombose Thérapies Réunion Océan Indien (DéTROI), 97490 Sainte-Clotilde, La Réunion, France.
Wildriss ViranaickenUniversité de La Réunion, UMR Processus Infectieux en Milieu Insulaire Tropical (PIMIT) INSERM 1187, CNRS 9192, 97490 Sainte-Clotilde, La Réunion, France.ORCID 0000-0002-0915-8635
Claude MarodonAPLAMEDOM Réunion, 1, rue Emile Hugot, Batiment B, Parc Technologique de Saint Denis, 97490 Sainte Clotilde, La Réunion, France.
Franck ReignierHabemus Papam, Food Industry, 97470 Saint-Benoit, La Réunion, France.
Christine Robert-Da SilvaUniversité de La Réunion, INSERM, UMR 1188 Diabète Athérothrombose Thérapies Réunion Océan Indien (DéTROI), 97490 Sainte-Clotilde, La Réunion, France.
Olivier MeilhacUniversité de La Réunion, INSERM, UMR 1188 Diabète Athérothrombose Thérapies Réunion Océan Indien (DéTROI), 97490 Sainte-Clotilde, La Réunion, France.ORCID 0000-0002-3740-7539
Inserm · FRCentre National de la Recherche Scientifique · FR

Funding

European Regional Development Fund RE0001897
6 · The paper itself

Abstract

Atherosclerosis is a hallmark of most cardiovascular diseases. The implication of macrophages in this pathology is widely documented, notably for their contribution to lipid accumulation within the arterial wall, associated with oxidative stress and inflammation processes. In order to prevent or limit the atherosclerosis damage, nutritional approaches and medicinal plant-based therapies need to be considered. In Reunion Island, medicinal plant-based beverages are traditionally used for their antioxidant, lipid-lowering and anti-inflammatory properties. The aim of our study was to assess the protective effects of eight medicinal plant decoctions in an in vitro model of RAW 264.7 murine macrophages exposed to pro-atherogenic conditions (oxidized low-density lipoproteins-ox-LDL-

Indexed as

AtherosclerosisPlants, MedicinalAnimalsAnti-Inflammatory AgentsCell SurvivalHumansLipopolysaccharidesLipoproteins, LDLMacrophagesMiceNF-kappa BPhytotherapyPlant ExtractsRAW 264.7 CellsReunionAnti-Inflammatory AgentsLipopolysaccharidesLipoproteins, LDLNF-kappa Boxidized low density lipoproteinPlant Extractsatherosclerosismedicinal plant decoctionpolyphenolsReunion Island

Identifiers

PMID33478034
PMCPMC7835778
OpenAlexW3123239336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.