ArticleAntibiotics (Basel, Switzerland)2021
Drivers of Broad-Spectrum Antibiotic Overuse across Diverse Hospital Contexts-A Qualitative Study of Prescribers in the UK, Sri Lanka and South Africa.
Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Phenotypic and genotypic landscape of antibiotic resistance through One Health approach in Sri Lanka: A systematic review.Tropical medicine & international health : TM & IH · 2025Pooled it
- Bacillus Subtilis THC1I Restores Intestinal Barrier Integrity and Gut Microbiota Balance in a Mouse Model of Antibiotic-Associated Diarrhea.Current microbiology · 2026Article
- Knowledge, Attitudes and Practices Related to Antimicrobial Use and Resistance Among Livestock Sector Stakeholders in Seven Former Soviet Countries: A Multi-Country Regional Analysis.Antibiotics (Basel, Switzerland) · 2026Article
- Antibiotic prescribing patterns and consumption at a comprehensive specialized hospital in northern Ethiopia: a prospective cross-sectional study underscoring the need for antimicrobial stewardship.BMC infectious diseases · 2026Article
- Antimicrobial Prescribing Practices for Surgical Prophylaxis in Caesarean Sections at Kawempe National Referral Hospital, Kampala, Uganda.Health science reports · 2026Article
- The latent system factors that influence antimicrobial use and governance in healthcare: a scoping review of high-income health systems.EClinicalMedicine · 2025Review
- Antimicrobial resistance, equity and justice in low- and middle-income countries: an intersectional critical interpretive synthesis.Nature communications · 2025Article
- Barriers in implementing antibiotic stewardship programmes at paediatric units in academic hospitals in Thailand: a qualitative study.BMJ open · 2025Article
- Antimicrobial resistance, antibiotic prescribing practices and antimicrobial stewardship in South Africa: a scoping review.JAC-antimicrobial resistance · 2025Review
- Antimicrobial stewardship challenges at a referral Hospital in Western Kenya: insights from a Kakamega-Cambridge health partnership.Frontiers in public health · 2025Article
- Impact of Antibiotic Stewardship on Treatment of Hospitalized Children with Skin and Soft-Tissue Infections.Children (Basel, Switzerland) · 2024Article
- An Overview of the Recent Advances in Antimicrobial Resistance.Microorganisms · 2024Review
- Navigating the Labyrinth: Intensive Care Challenges for Patients with Acute-on-Chronic Liver Failure.Journal of clinical medicine · 2024Review
- Unveiling the menace: a thorough review of potential pandemic fungal disease.Frontiers in fungal biology · 2024Review
- Hospital Pharmacists' Viewpoint on Quality Use of Antibiotics and Resistance: A Qualitative Exploration from a Tertiary Care Hospital of Quetta City, Pakistan.Antibiotics (Basel, Switzerland) · 2023Article
- Investigating the evolution and predicting the future outlook of antimicrobial resistance in sub-saharan Africa using phenotypic data for Klebsiella pneumoniae: a 12-year analysis.BMC microbiology · 2023Article
- Identify Drug-Resistant Pathogens in Patients with Community-Acquired Pneumonia.Advances in respiratory medicine · 2023Review
- Pattern of Antibiotic Use among Hospitalized Patients at a Level One Multidisciplinary Care Hospital.Healthcare (Basel, Switzerland) · 2023Article
- Overuse of medications in low- and middle-income countries: a scoping review.Bulletin of the World Health Organization · 2023Article
- Mixed methods study protocol for combining stakeholder-led rapid evaluation with near real-time continuous registry data to facilitate evaluations of quality of care in intensive care units.Wellcome open research · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
Antimicrobial stewardship programs focus on reducing overuse of broad-spectrum antibiotics (BSAs), primarily through interventions to change prescribing behavior. This study aims to identify multi-level influences on BSA overuse across diverse high and low income, and public and private, healthcare contexts. Semi-structured interviews were conducted with 46 prescribers from hospitals in the UK, Sri Lanka, and South Africa, including public and private providers. Interviews explored decision making about prescribing BSAs, drivers of the use of BSAs, and benefits of BSAs to various stakeholders, and were analyzed using a constant comparative approach. Analysis identified drivers of BSA overuse at the individual, social and structural levels. Structural drivers of overuse varied significantly across contexts and included: system-level factors generating tensions with stewardship goals; limited material resources within hospitals; and patient poverty, lack of infrastructure and resources in local communities. Antimicrobial stewardship needs to encompass efforts to reduce the reliance on BSAs as a solution to context-specific structural conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.