Evidence map›Paper›PMID 33477910›Full record

ReviewMicroorganisms2021

Fungal Endophytes as Efficient Sources of Plant-Derived Bioactive Compounds and Their Prospective Applications in Natural Product Drug Discovery: Insights, Avenues, and Challenges.

Archana Singh, Dheeraj K Singh, Ravindra N Kharwar, James F White, Surendra K Gond

Abstract readReview
In one paragraph

Review in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  15. Harnessing endophytes and Multi-Omics for sustainable Colchicine biosynthesis.World journal of microbiology & biotechnology · 2026
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Archana SinghDepartment of Botany, MMV, Banaras Hindu University, Varanasi 221005, India.
Dheeraj K SinghDepartment of Botany, Harish Chandra Post Graduate College, Varanasi 221001, India.ORCID 0000-0002-2737-9028
Ravindra N KharwarDepartment of Botany, Institute of Science, Banaras Hindu University, Varanasi 221005, India.ORCID 0000-0002-6780-7066
James F WhiteDepartment of Plant Biology, Rutgers University, New Brunswick, NJ 08901, USA.
Surendra K GondDepartment of Botany, MMV, Banaras Hindu University, Varanasi 221005, India.

Funding

Science and Engineering Research Board EEQ/2016/000555 and EEQ/2020/000485USDA NIFA W-4147
6 · The paper itself

Abstract

Fungal endophytes are well-established sources of biologically active natural compounds with many producing pharmacologically valuable specific plant-derived products. This review details typical plant-derived medicinal compounds of several classes, including alkaloids, coumarins, flavonoids, glycosides, lignans, phenylpropanoids, quinones, saponins, terpenoids, and xanthones that are produced by endophytic fungi. This review covers the studies carried out since the first report of taxol biosynthesis by endophytic

Indexed as

bioactivedrug discoveryendophytic fungihost-derivedmedicinal plantsnatural productsplant-derivedsecondary metabolites

Identifiers

PMID33477910
PMCPMC7833388

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.