Evidence map›Paper›PMID 33477898›Full record

ArticleInternational journal of molecular sciences2021

De Novo Profiling of Long Non-Coding RNAs Involved in MC-LR-Induced Liver Injury in Whitefish: Discovery and Perspectives.

Maciej Florczyk, Paweł Brzuzan, Maciej Woźny

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maciej FlorczykDepartment of Environmental Biotechnology, Faculty of Geoengineering, University of Warmia and Mazury in Olsztyn, ul. Słoneczna 45G, 10-709 Olsztyn, Poland.ORCID 0000-0003-2277-312X
Paweł BrzuzanDepartment of Environmental Biotechnology, Faculty of Geoengineering, University of Warmia and Mazury in Olsztyn, ul. Słoneczna 45G, 10-709 Olsztyn, Poland.
Maciej WoźnyDepartment of Environmental Biotechnology, Faculty of Geoengineering, University of Warmia and Mazury in Olsztyn, ul. Słoneczna 45G, 10-709 Olsztyn, Poland.ORCID 0000-0001-5201-2925
University of Warmia and Mazury in Olsztyn · PL

Funding

National Science Centre of Poland 2016/21/B/NZ9/03566
6 · The paper itself

Abstract

Microcystin-LR (MC-LR) is a potent hepatotoxin for which a substantial gap in knowledge persists regarding the underlying molecular mechanisms of liver toxicity and injury. Although long non-coding RNAs (lncRNAs) have been extensively studied in model organisms, our knowledge concerning the role of lncRNAs in liver injury is limited. Given that lncRNAs show low levels of sequence conservation, their role becomes even more unclear in non-model organisms without an annotated genome, like whitefish (

Indexed as

AnimalsChemical and Drug Induced Liver Injury, ChronicFish DiseasesLiverMarine ToxinsMicrocystinsMicroRNAsMolecular Sequence AnnotationRNA, Long NoncodingRNA, MessengerSalmonidaeSequence Analysis, RNATranscriptomecyanoginosin LRMarine ToxinsMicrocystinsMicroRNAsRNA, Long NoncodingRNA, Messengerautonomous 3′UTRsbiomarkerceRNAsde novodrug-induced liver injuryliver transcriptomelncRNAsMALAT1non-coding RNAs

Identifiers

PMID33477898
PMCPMC7833382
OpenAlexW3125087710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.