Evidence map›Paper›PMID 33477709›Full record

ReviewMolecules (Basel, Switzerland)2021

Plant Secondary Metabolites: An Opportunity for Circular Economy.

Ilaria Chiocchio, Manuela Mandrone, Paola Tomasi, Lorenzo Marincich, Ferruccio Poli

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 3 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 3 syntheses or guidelines pooled it, 199 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Novel indole alkaloids from the flower buds ofJournal of ginseng research · 2026
    Article
  5. Article
  6. Review
  7. Selenium biofortification: integrating one health and sustainability.Journal of the science of food and agriculture · 2026
    Review
  8. Review
  9. Valorization of Turnip Greens (Molecules (Basel, Switzerland) · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Molecules (Basel, Switzerland) · 2025
    Article
  18. Review
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ilaria ChiocchioDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Irnerio 42, 40126 Bologna, Italy.ORCID 0000-0001-6171-278X
Manuela MandroneDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Irnerio 42, 40126 Bologna, Italy.ORCID 0000-0002-0541-390X
Paola TomasiDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Irnerio 42, 40126 Bologna, Italy.
Lorenzo MarincichDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Irnerio 42, 40126 Bologna, Italy.ORCID 0000-0001-6343-8606
Ferruccio PoliDepartment of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Irnerio 42, 40126 Bologna, Italy.ORCID 0000-0002-2660-7711
University of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Moving toward a more sustainable development, a pivotal role is played by circular economy and a smarter waste management. Industrial wastes from plants offer a wide spectrum of possibilities for their valorization, still being enriched in high added-value molecules, such as secondary metabolites (SMs). The current review provides an overview of the most common SM classes (chemical structures, classification, biological activities) present in different plant waste/by-products and their potential use in various fields. A bibliographic survey was carried out, taking into account 99 research articles (from 2006 to 2020), summarizing all the information about waste type, its plant source, industrial sector of provenience, contained SMs, reported bioactivities, and proposals for its valorization. This survey highlighted that a great deal of the current publications are focused on the exploitation of plant wastes in human healthcare and food (including cosmetic, pharmaceutical, nutraceutical and food additives). However, as summarized in this review, plant SMs also possess an enormous potential for further uses. Accordingly, an increasing number of investigations on neglected plant matrices and their use in areas such as veterinary science or agriculture are expected, considering also the need to implement "greener" practices in the latter sector.

Indexed as

AgricultureDietary SupplementsEconomic DevelopmentHumansPlantsWaste ManagementWaste ProductsWaste Productsbioactivitiescircular economynatural productsplant by-productsplant secondary metaboliteswaste valorization

Identifiers

PMID33477709
PMCPMC7831927
OpenAlexW3125286344

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.