Evidence map›Paper›PMID 33477687›Full record

ReviewInternational journal of molecular sciences2021

Functions of Muscarinic Receptor Subtypes in Gastrointestinal Smooth Muscle: A Review of Studies with Receptor-Knockout Mice.

Yasuyuki Tanahashi, Seiichi Komori, Hayato Matsuyama, Takio Kitazawa, Toshihiro Unno

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 65 citations in OpenAlex.

  1. Nutrients · 2026
    Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Nutrients · 2026
    Article
  7. Article
  8. Decoding Barberry Root's Therapeutic Network: A Synergistic Solution for IBS-D.Combinatorial chemistry & high throughput screening · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Obesity and Gut-Brain Communication: The Cholinergic-Endocannabinoid Link.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  14. Article
  15. Conditional deletion of IPJournal of gastroenterology · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. 2-Amino-Molecules (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Yasuyuki TanahashiDepartment of Advanced Life Sciences, Faculty of Life Sciences, Kyoto Sangyo University, Kyoto 603-8555, Japan.ORCID 0000-0003-0394-1765
Seiichi KomoriLaboratory of Veterinary Pharmacology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
Hayato MatsuyamaLaboratory of Veterinary Pharmacology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
Takio KitazawaDepartment of Veterinary Science, Rakuno Gakuen University, Ebetsu, Hokkaido 069-8501, Japan.
Toshihiro UnnoLaboratory of Veterinary Pharmacology, Department of Veterinary Medicine, Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.
Gifu University · JPKyoto Sangyo University · JPRakuno Gakuen University · JP

Funding

Japan Society for the Promotion of Science 15K07765Japan Society for the Promotion of Science 16380199Japan Society for the Promotion of Science 17580253Japan Society for the Promotion of Science 17K08076Japan Society for the Promotion of Science 22380159Japan Society for the Promotion of Science 25870891Japan Society for the Promotion of Science 26450402the JSPS Research Fellows for Young Scientists 203080
6 · The paper itself

Abstract

Parasympathetic signalling via muscarinic acetylcholine receptors (mAChRs) regulates gastrointestinal smooth muscle function. In most instances, the mAChR population in smooth muscle consists mainly of M

Indexed as

AnimalsGastrointestinal TractGTP-Binding ProteinsMiceMice, KnockoutMuscle ContractionMuscle, SmoothReceptor, Muscarinic M2Receptor, Muscarinic M3Signal TransductionGTP-Binding ProteinsReceptor, Muscarinic M2Receptor, Muscarinic M3gastrointestinal tractknockout mousemuscarinic receptor subtypesnon-selective cationic channelssignal transduction pathwayssmooth muscle

Identifiers

PMID33477687
PMCPMC7831928
OpenAlexW3125671097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.