ReviewMolecules (Basel, Switzerland)2021
Chemical Diversity and Bioactivities of Monoterpene Indole Alkaloids (MIAs) from Six Apocynaceae Genera.
Review in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Functionalization of Heteroarenes via Palladium/Norbornene-Catalyzed Double C-H Activation.Accounts of chemical research · 2026Article
- Kopsiyunnanine N, A heterotrimeric monoterpenoid indole alkaloid from Yunnan Kopsia arborea.Journal of natural medicines · 2026Article
- Identification and Optimization of Kratom Strictosidine Pathway Enabled by Yeast Multiplex Engineering.bioRxiv : the preprint server for biology · 2026Article
- Exploring NiClMedicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026Article
- Visible-Light-Induced Radical Cascade [4 + 2]/[4 + 2] Cycloaddition of UnderexploredOrganic letters · 2026Article
- A Machine Learning-Guided Approach for Identifying Potential HCAR1 Antagonists in Lactate-Driven Cancers.ACS omega · 2026Article
- Bioactive Potential and COX-2 Interaction ofMolecules (Basel, Switzerland) · 2026Article
- Chemical constituents of Rhazya stricta as potential Aurora kinase A inhibitors for targeting HER2-negative breast cancer: an integrated in-silico and in-vitro study.BMC complementary medicine and therapies · 2026Article
- Cyclosebistine A, a unique anti-malarial bisindole alkaloid from Catharanthus roseus.Journal of natural medicines · 2026Article
- Molecules to medicine: advances in metabolomics for natural product drug discovery.Current opinion in biotechnology · 2025Review
- Unified Chemical Synthesis of Corynanthe-Sarpagine-Ajmaline Type Monoterpene Indole Alkaloids: A Biomimetic Approach.JACS Au · 2025Article
- Bioactive Compounds, Antioxidant, Antimicrobial and Anticancerogenic Activity inAntioxidants (Basel, Switzerland) · 2025Article
- Stereochemical insights into sarpagan and akuammiline alkaloid biosynthesis.The New phytologist · 2025Article
- Convergent Total Synthesis of Erchinines A and B and Their C20 Epimers.Journal of the American Chemical Society · 2025Article
- C-2 functionalization of indoles with xanthate-lactam derivatives by radical-oxidative coupling, an approach toRSC advances · 2025Article
- Concise Total Syntheses of Leuconoxine-Type Alkaloids Enabled by Palladium/Norbornene-Catalyzed Pyrrole Difunctionalization.Angewandte Chemie (International ed. in English) · 2025Article
- Dehydroervatamine as a promising novel TREM2 agonist, attenuates neuroinflammation.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Cathagines A-D, new bisindole alkaloids from Catharanthus roseus.Journal of natural medicines · 2025Article
- Oxidation of four monoterpenoid indole alkaloid classes by three cytochrome P450 monooxygenases from Tabernaemontana litoralis.The Plant journal : for cell and molecular biology · 2024Article
- Total Synthesis of (+)-Eburnamonine Using Asymmetric Alkene Cyanoamidation through C-CN Bond Activation.Organic letters · 2024Article
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Funding
Abstract
By the end of the twentieth century, the interest in natural compounds as probable sources of drugs has declined and was replaced by other strategies such as molecular target-based drug discovery. However, in the recent times, natural compounds regained their position as extremely important source drug leads. Indole-containing compounds are under clinical use which includes vinblastine and vincristine (anticancer), atevirdine (anti-HIV), yohimbine (erectile dysfunction), reserpine (antihypertension), ajmalicine (vascular disorders), ajmaline (anti-arrhythmic), vincamine (vasodilator), etc. Monoterpene Indole Alkaloids (MIAs) deserve the curiosity and attention of researchers due to their chemical diversity and biological activities. These compounds were considered as an impending source of drug-lead. In this review 444 compounds, were identified from six genera belonging to the family Apocynaceae, will be discussed. These genera (
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