Evidence map›Paper›PMID 33477656›Full record

ArticleSensors (Basel, Switzerland)2021

Hyperspectral Imagery for Assessing Laser-Induced Thermal State Change in Liver.

Martina De Landro, Ignacio Espíritu García-Molina, Manuel Barberio, Eric Felli, Vincent Agnus, Margherita Pizzicannella, Michele Diana, Emanuele Zappa, Paola Saccomandi

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Interstitial Optical Monitoring of Focal Laser Ablation.IEEE transactions on bio-medical engineering · 2022
    Article
  6. Review
  7. Article
  8. Thermal analysis of laser irradiation-gold nanorod combinations at 808 nm, 940 nm, 975 nm and 1064 nm wavelengths in breast cancer model.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Martina De LandroDepartment of Mechanical Engineering, Politecnico di Milano, 20156 Milan, Italy.ORCID 0000-0002-1778-8928
Ignacio Espíritu García-MolinaDepartment of Mechanical Engineering, Politecnico di Milano, 20156 Milan, Italy.ORCID 0000-0002-5579-5926
Manuel BarberioIHU-Strasbourg, 67000 Strasbourg, France.ORCID 0000-0002-8241-6442
Eric FelliIHU-Strasbourg, 67000 Strasbourg, France.ORCID 0000-0002-5664-6746
Vincent AgnusIHU-Strasbourg, 67000 Strasbourg, France.ORCID 0000-0001-9554-6492
Margherita PizzicannellaIHU-Strasbourg, 67000 Strasbourg, France.
Michele DianaIHU-Strasbourg, 67000 Strasbourg, France.
Emanuele ZappaDepartment of Mechanical Engineering, Politecnico di Milano, 20156 Milan, Italy.ORCID 0000-0003-3320-9030
Paola SaccomandiDepartment of Mechanical Engineering, Politecnico di Milano, 20156 Milan, Italy.ORCID 0000-0003-4236-8033
Institut de Chirurgie Guidée par l'Image · FRPolitecnico di Milano · ITLaboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie · FR

Funding

ARC Foundation for Cancer Research ELIOSH2020 European Research Council 759159
6 · The paper itself

Abstract

This work presents the potential of hyperspectral imaging (HSI) to monitor the thermal outcome of laser ablation therapy used for minimally invasive tumor removal. Our main goal is the establishment of indicators of the thermal damage of living tissues, which can be used to assess the effect of the procedure. These indicators rely on the spectral variation of temperature-dependent tissue chromophores, i.e., oxyhemoglobin, deoxyhemoglobin, methemoglobin, and water. Laser treatment was performed at specific temperature thresholds (from 60 to 110 °C) on in-vivo animal liver and was assessed with a hyperspectral camera (500-995 nm) during and after the treatment. The indicators were extracted from the hyperspectral images after the following processing steps: the breathing motion compensation and the spectral and spatial filtering, the selection of spectral bands corresponding to specific tissue chromophores, and the analysis of the areas under the curves for each spectral band. Results show that properly combining spectral information related to deoxyhemoglobin, methemoglobin, lipids, and water allows for the segmenting of different zones of the laser-induced thermal damage. This preliminary investigation provides indicators for describing the thermal state of the liver, which can be employed in the future as clinical endpoints of the procedure outcome.

Indexed as

LasersLaser TherapyAnimalsLightLiverTemperaturehyperspectral imagingimage processingimage segmentationlaser ablationmethemoglobintemperature-dependent tissue chromophoresthermal damagetissue chromophores

Identifiers

PMID33477656
PMCPMC7831494
OpenAlexW3121647686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.