Evidence map›Paper›PMID 33477618›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Quantification of Nitric Oxide Concentration Using Single-Walled Carbon Nanotube Sensors.

Jakob Meier, Joseph Stapleton, Eric Hofferber, Abigail Haworth, Stephen Kachman, Nicole M Iverson

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Near-Infrared Fluorescent Single-Walled Carbon Nanotubes for Biosensing.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Biosensing with Fluorescent Carbon Nanotubes.Angewandte Chemie (International ed. in English) · 2022
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jakob MeierDepartment of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Joseph StapletonDepartment of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Eric HofferberDepartment of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Abigail HaworthDepartment of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Stephen KachmanDepartment of Statistics, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
Nicole M IversonDepartment of Biological Systems Engineering, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.
University of Nebraska–Lincoln · US

Funding

Nebraska Center for Nanomedicine- Pilot ProjectsP30GM127200 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BRONICH, TATIANA K · 2018 to 2022
$5.7M
National Science Foundation OIA-1557417NIH HHS P30 GM127200
6 · The paper itself

Abstract

Nitric oxide (NO), a free radical present in biological systems, can have many detrimental effects on the body, from inflammation to cancer. Due to NO's short half-life, detection and quantification is difficult. The inability to quantify NO has hindered researchers' understanding of its impact in healthy and diseased conditions. Single-walled carbon nanotubes (SWNTs), when wrapped in a specific single-stranded DNA chain, becomes selective to NO, creating a fluorescence sensor. Unfortunately, the correlation between NO concentration and the SWNT's fluorescence intensity has been difficult to determine due to an inability to immobilize the sensor without altering its properties. Through the use of a recently developed sensor platform, systematic studies can now be conducted to determine the correlation between SWNT fluorescence and NO concentration. This paper explains the methods used to determine the equations that can be used to convert SWNT fluorescence into NO concentration. Through the use of the equations developed in this paper, an easy method for NO quantification is provided. The methods outlined in this paper will also enable researchers to develop equations to determine the concentration of other reactive species through the use of SWNT sensors.

Indexed as

carbon nanotube sensorsconcentration quantificationnitric oxidereactive speciesspatial detectiontemporal detection

Identifiers

PMID33477618
PMCPMC7831316
OpenAlexW3124554540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.