Evidence map›Paper›PMID 33477551›Full record

ArticleCells2021

A Splice Variant in

Laurence Klipfel, Marie Cordonnier, Léa Thiébault, Emmanuelle Clérin, Frédéric Blond, Géraldine Millet-Puel, Saddek Mohand-Saïd, Olivier Goureau, José-Alain Sahel, Emeline F Nandrot and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. The Retinal Pigment Epithelium: Cells That Know the Beat!Advances in experimental medicine and biology · 2023
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Laurence KlipfelInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.
Marie CordonnierInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.
Léa ThiébaultInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.
Emmanuelle ClérinInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.
Frédéric BlondInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.ORCID 0000-0002-2314-0570
Géraldine Millet-PuelInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.
Saddek Mohand-SaïdCHNO des Quinze-Vingts, INSERM-DGOS CIC 1423, 28 rue de Charenton, F-75012 Paris, France.
Olivier GoureauInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.
José-Alain SahelInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.
Emeline F NandrotInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.
Thierry LéveillardInstitut de la Vision, CNRS, INSERM, Sorbonne Université, 17 rue Moreau, F-75012 Paris, France.
Centre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related macular degeneration (AMD) is a blinding disease for which most of the patients remain untreatable. Since the disease affects the macula at the center of the retina, a structure specific to the primate lineage, rodent models to study the pathophysiology of AMD and to develop therapies are very limited. Consequently, our understanding relies mostly on genetic studies highlighting risk alleles at many loci. We are studying the possible implication of a metabolic imbalance associated with risk alleles within the

Indexed as

Alternative SplicingBiological Transport, ActiveEpithelial CellsHumansInduced Pluripotent Stem CellsLactic AcidMacular DegenerationMonocarboxylic Acid TransportersRetinal Pigment EpitheliumLactic AcidMonocarboxylic Acid Transportersage-related macular degenerationinduced pluripotent stem cellslactate transportMCT3retinal pigment epitheliumsplicing

Identifiers

PMID33477551
PMCPMC7831140
OpenAlexW3125900439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.