Evidence map›Paper›PMID 33477307›Full record

ArticleFoods (Basel, Switzerland)2021

Colon Bioaccessibility under In Vitro Gastrointestinal Digestion of Different Coffee Brews Chemically Profiled through UHPLC-Q-Orbitrap HRMS.

Luigi Castaldo, Luana Izzo, Alfonso Narváez, Yelko Rodríguez-Carrasco, Michela Grosso, Alberto Ritieni

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Effect of Cooking andFoods (Basel, Switzerland) · 2025
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  12. Analysis of Polyphenolic Compounds in Water-Based Extracts ofAntioxidants (Basel, Switzerland) · 2022
    Article
  13. Chemical Composition of Green Pea (Antioxidants (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Luigi CastaldoDepartment of Pharmacy, University of Naples "Federico II", 49 Domenico Montesano Street, 80131 Naples, Italy.ORCID 0000-0001-6883-9396
Luana IzzoDepartment of Pharmacy, University of Naples "Federico II", 49 Domenico Montesano Street, 80131 Naples, Italy.ORCID 0000-0002-8365-9032
Alfonso NarváezDepartment of Pharmacy, University of Naples "Federico II", 49 Domenico Montesano Street, 80131 Naples, Italy.ORCID 0000-0002-4328-2330
Yelko Rodríguez-CarrascoLaboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av. Vicent Andrés Estellés s/n, Burjassot, 46100 València, Spain.ORCID 0000-0002-6421-218X
Michela GrossoDepartment of Molecular Medicine and Medical Biotechnology, School of Medicine, University of Naples "Federico II", CEINGE-Biotecnologie Avanzate, 80131 Naples, Italy.ORCID 0000-0003-1664-1657
Alberto RitieniDepartment of Pharmacy, University of Naples "Federico II", 49 Domenico Montesano Street, 80131 Naples, Italy.ORCID 0000-0003-0314-8839
University of Naples Federico II · ITCeinge Biotecnologie Avanzate (Italy) · ITFederico II University Hospital · ITUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coffee represents one of the most traditionally consumed beverages worldwide, containing a broad range of human health-related compounds. According to previous studies, regular coffee consumption may display protective effects against colorectal cancer and other chronic diseases. The main goal of this research was to evaluate the bioaccessibility of phenolic content and variation in antioxidant capacity of three different types of coffee brews after simulated gastrointestinal digestion. This would allow to elucidate how antioxidant compounds present in coffee may exert their effect on the human body, especially in the colonic stage. Moreover, the content of bioactive compounds namely chlorogenic acids (CGAs,

Indexed as

bioaccessibilitychlorogenic acidscoffeein vitro gastrointestinal digestionpolyphenols

Identifiers

PMID33477307
PMCPMC7829986
OpenAlexW3125690701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.