Evidence map›Paper›PMID 33477268›Full record

ArticleJournal of clinical medicine2021

Prognostic Implications of Chronic Heart Failure and Utility of NT-proBNP Levels in Heart Failure Patients with SARS-CoV-2 Infection.

Laia C Belarte-Tornero, Sandra Valdivielso-Moré, Miren Vicente Elcano, Eduard Solé-González, Sonia Ruíz-Bustillo, Alicia Calvo-Fernández, Isaac Subinara, Paula Cabero, Cristina Soler, Héctor Cubero-Gallego and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 5 pooled it
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Laia C Belarte-TorneroHeart Failure Unit, Department of Cardiology, Hospital del Mar, 08003 Barcelona, Spain.ORCID 0000-0003-2774-1290
Sandra Valdivielso-MoréHeart Failure Unit, Department of Cardiology, Hospital del Mar, 08003 Barcelona, Spain.
Miren Vicente ElcanoDepartment of Cardiology, Hospital del Mar, 08003 Barcelona, Spain.
Eduard Solé-GonzálezHeart Failure Unit, Department of Cardiology, Hospital del Mar, 08003 Barcelona, Spain.ORCID 0000-0002-5727-9925
Sonia Ruíz-BustilloHeart Failure Unit, Department of Cardiology, Hospital del Mar, 08003 Barcelona, Spain.
Alicia Calvo-FernándezHeart Failure Unit, Department of Cardiology, Hospital del Mar, 08003 Barcelona, Spain.ORCID 0000-0001-6504-3528
Isaac SubinaraCIBER Epidemiology and Public Health, IMIM-Parc de Salut Mar, 08003 Barcelona, Spain.
Paula CaberoHeart Diseases Biomedical Research Group (GREC), IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, Spain.
Cristina SolerHeart Diseases Biomedical Research Group (GREC), IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, Spain.
Héctor Cubero-GallegoHeart Diseases Biomedical Research Group (GREC), IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, Spain.
Beatriz VaquerizoHeart Diseases Biomedical Research Group (GREC), IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, Spain.
Núria FarréHeart Failure Unit, Department of Cardiology, Hospital del Mar, 08003 Barcelona, Spain.
Hospital Del Mar · ESUniversitat Autònoma de Barcelona · ESParc de Salut · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence and prognostic value of chronic heart failure (CHF) in the setting of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection has seldom been studied. The aim of this study was to analyze the prevalence and prognosis of CHF in this setting.

methodsThis single-center study included 829 consecutive patients with SARS-CoV-2 infection from February to April 2020. Patients with a previous history of CHF were matched 1:2 for age and sex. We analyze the prognostic value of pre-existing CHF. Prognostic implications of N terminal pro brain natriuretic peptide (NT-proBNP) levels on admission in the CHF cohort were explored.

resultsA total of 129 patients (43 CHF and 86 non-CHF) where finally included. All-cause mortality was higher in CHF patients compared to non-CHF patients (51.2% vs. 29.1%,

conclusionsAll-cause mortality in CHF patients hospitalized due to SARS-CoV-2 infection was 51.2%. CHF was independently associated with all-cause mortality (HR 2.3, CI 95% 1.26-4.2). NT-proBNP levels could be used for stratification risk purposes to guide medical decisions if larger studies confirm this finding.

Indexed as

biomarkerscoronavirusCOVID-19heart failureNT-proBNPprognosisSARS-CoV-2troponin

Identifiers

PMID33477268
PMCPMC7829899
OpenAlexW3121282563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.