Evidence map›Paper›PMID 33477094›Full record

ReviewCurrent opinion in neurobiology2021

Familiar growth factors have diverse roles in neural network assembly.

Caitlin A Short, Massimo M Onesto, Sarah K Rempel, Timothy S Catlett, Timothy M Gomez

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023
    Article
  7. FGF3 Directs the Pathfinding of Prethalamic GABAergic Axons.International journal of molecular sciences · 2023
    Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Caitlin A ShortDepartment of Neuroscience and Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, United States.
Massimo M OnestoDepartment of Neuroscience and Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, United States; Stanford University School of Medicine, United States.
Sarah K RempelDepartment of Neuroscience and Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, United States.
Timothy S CatlettDepartment of Neuroscience and Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, United States.
Timothy M GomezDepartment of Neuroscience and Neuroscience Training Program, University of Wisconsin, Madison, WI 53706, United States. Electronic address: tmgomez@wisc.edu.
University of Wisconsin–Madison · USUniversity of Wisconsin System · US

Funding

NEUROSCIENCE TRAINING PROGRAMT32GM007507 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI HALLORAN, MARY C · 1985 to 2017
$9.3M
Mechanisms of mTOR-independent axon growth and guidance defects in TSC2 mutant human neuronsR01NS113314 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2020 to 2024
$1.8M
Vision Research Training ProgramT32EY027721 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI ROBERT W NICKELLS · 2018 to 2026
$1.5M
Molecular mechanisms of growth cone invasionR01NS099405 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2016 to 2019
$1.4M
NEUROBIOLOGY OF BRAIN ARGININE DECARBOXYLASER01NS039445 · NINDS · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI REGUNATHAN, SOUNDAR · 2000 to 2003
$976k
Molecular mechanisms of abnormal dendritic spine development and function in human neurons with TSC2 disease mutationsR21NS125419 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI GOMEZ, TIMOTHY M · 2021 to 2021
$408k
NEI NIH HHS T32 EY027721NIGMS NIH HHS T32 GM007507NINDS NIH HHS R01 NS039445NINDS NIH HHS R01 NS099405NINDS NIH HHS R01 NS113314NINDS NIH HHS R21 NS125419
6 · The paper itself

Abstract

The assembly of neuronal circuits during development depends on guidance of axonal growth cones by molecular cues deposited in their environment. While a number of families of axon guidance molecules have been identified and reviewed, important and diverse activities of traditional growth factors are emerging. Besides clear and well recognized roles in the regulation of cell division, differentiation and survival, new research shows later phase roles for a number of growth factors in promoting neuronal migration, axon guidance and synapse formation throughout the nervous system.

Indexed as

Axon GuidanceGrowth ConesAxonsNervous SystemNeural Networks, ComputerNeurons

Identifiers

PMID33477094
PMCPMC8058242
OpenAlexW3122338149

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.