Evidence map›Paper›PMID 33476391›Full record

ReviewNeurosurgery2021

Central Nervous System Plasticity Influences Language and Cognitive Recovery in Adult Glioma.

Saritha Krishna, Sofia Kakaizada, Nyle Almeida, David Brang, Shawn Hervey-Jumper

Open access · greenAbstract readReview
In one paragraph

Review in Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  13. Neural Signaling in Cancer.Annual review of neuroscience · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Saritha KrishnaDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, California.
Sofia KakaizadaDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, California.
Nyle AlmeidaDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, California.
David BrangDepartment of Psychology, University of Michigan, Ann Arbor, Michigan.
Shawn Hervey-JumperDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, California.ORCID 0000-0003-4699-260X
University of California, San Francisco · USUniversity of Michigan · US

Funding

Intratumoral functional connectivity with implications on synaptogenesis and aphasia recovery in adult astrocytic WHO II-III gliomaK08NS110919 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HERVEY-JUMPER, SHAWN L. · 2019 to 2023
$1.0M
NCI NIH HHS L30 CA199570NINDS NIH HHS K08 NS110919
6 · The paper itself

Abstract

Gliomas exist within the framework of complex neuronal circuitry in which network dynamics influence both tumor biology and cognition. The generalized impairment of cognition or loss of language function is a common occurrence for glioma patients. The interface between intrinsic brain tumors such as gliomas and functional cognitive networks are poorly understood. The ability to communicate effectively is critically important for receiving oncological therapies and maintaining a high quality of life. Although the propensity of gliomas to infiltrate cortical and subcortical structures and disrupt key anatomic language pathways is well documented, there is new evidence offering insight into the network and cellular mechanisms underpinning glioma-related aphasia and aphasia recovery. In this review, we will outline the current understanding of the mechanisms of cognitive dysfunction and recovery, using aphasia as an illustrative model.

Indexed as

Brain NeoplasmsGliomaAdultBrain MappingCentral Nervous SystemCognitionHumansLanguageQuality of LifeAphasiaCognitionGliomaLanguageNeurogenesisPlasticityRadiation

Identifiers

PMID33476391
PMCPMC8440067
OpenAlexW3126106134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.