ArticlePLoS computational biology2021
Post-lockdown abatement of COVID-19 by fast periodic switching.
Article in PLoS computational biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Optimal algorithms for controlling infectious diseases in real time using noisy infection data.PLoS computational biology · 2025Article
- Optimal strategies for coordinating infection control and socio-economic activities.Mathematics and computers in simulation · 2023Article
- Optimal non-pharmaceutical pandemic response strategies depend critically on time horizons and costs.Scientific reports · 2023Article
- Decision analysis of international joint prevention and control of public health emergencies.Environment, development and sustainability · 2022Article
- Epidemiological model based periodic intervention policies for COVID-19 mitigation in the United Kingdom.Scientific reports · 2022Article
- Assessing impact of the COVID-19 pandemic on China's TFP growth: Evidence from region-level data in 2020.Economic analysis and policy · 2022Article
- Optimal intervention strategies to mitigate the COVID-19 pandemic effects.Scientific reports · 2022Article
- Estimating the generation interval from the incidence rate, the optimal quarantine duration and the efficiency of fast switching periodic protocols for COVID-19.Scientific reports · 2022Article
- Influence of state reopening policies in COVID-19 mortality.Scientific reports · 2022Article
- Age structure in SIRD models for the COVID-19 pandemic-A case study on Italy data and effects on mortality.PloS one · 2022Article
- Activity-driven network modeling and control of the spread of two concurrent epidemic strains.Applied network science · 2022Article
- Modeling vaccination rollouts, SARS-CoV-2 variants and the requirement for non-pharmaceutical interventions in Italy.Nature medicine · 2021Article
- Modeling COVID-19 Nonpharmaceutical Interventions: Exploring periodic NPI strategies.medRxiv : the preprint server for health sciences · 2021Article
- A novel COVID-19 epidemiological model with explicit susceptible and asymptomatic isolation compartments reveals unexpected consequences of timing social distancing.Journal of theoretical biology · 2021Article
- Could periodic nonpharmaceutical intervention strategies produce better COVID-19 health and economic outcomes?Policy and complex systems · 2021Article
- Hysteresis-based supervisory control with application to non-pharmaceutical containment of COVID-19.Annual reviews in control · 2021Article
- Estimation of exogenous drivers to predict COVID-19 pandemic using a method from nonlinear control theory.Nonlinear dynamics · 2021Article
- Data-driven methods for present and future pandemics: Monitoring, modelling and managing.Annual reviews in control · 2021Review
- Optimized Lockdown Strategies for Curbing the Spread of COVID-19: A South African Case Study.IEEE access : practical innovations, open solutions · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
COVID-19 abatement strategies have risks and uncertainties which could lead to repeating waves of infection. We show-as proof of concept grounded on rigorous mathematical evidence-that periodic, high-frequency alternation of into, and out-of, lockdown effectively mitigates second-wave effects, while allowing continued, albeit reduced, economic activity. Periodicity confers (i) predictability, which is essential for economic sustainability, and (ii) robustness, since lockdown periods are not activated by uncertain measurements over short time scales. In turn-while not eliminating the virus-this fast switching policy is sustainable over time, and it mitigates the infection until a vaccine or treatment becomes available, while alleviating the social costs associated with long lockdowns. Typically, the policy might be in the form of 1-day of work followed by 6-days of lockdown every week (or perhaps 2 days working, 5 days off) and it can be modified at a slow-rate based on measurements filtered over longer time scales. Our results highlight the potential efficacy of high frequency switching interventions in post lockdown mitigation. All code is available on Github at https://github.com/V4p1d/FPSP_Covid19. A software tool has also been developed so that interested parties can explore the proof-of-concept system.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.