Evidence map›Paper›PMID 33475996›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2021

Quantitative Assessment of Renal Perfusion and Oxygenation by Invasive Probes: Basic Concepts.

Kathleen Cantow, Roger G Evans, Dirk Grosenick, Thomas Gladytz, Thoralf Niendorf, Bert Flemming, Erdmann Seeliger

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. [A high temporal resolution dynamic TNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  2. Magnetic resonance imaging of renal oxygenation.Nature reviews. Nephrology · 2025
    Review
  3. Renal MRI: From Nephron to NMR Signal.Journal of magnetic resonance imaging : JMRI · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kathleen CantowWorking Group Integrative Kidney Physiology, Institute of Physiology, Charité-University Medicine Berlin, Berlin, Germany.
Roger G EvansCardiovascular Disease Program, Biomedicine Discovery Institute and Department of Physiology, Monash University, Melbourne, Australia.
Dirk GrosenickPhysikalisch-Technische Bundesanstalt (German Federal Metrologic Institute), Berlin, Germany.
Thomas GladytzPhysikalisch-Technische Bundesanstalt (German Federal Metrologic Institute), Berlin, Germany.
Thoralf NiendorfBerlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine (MDC) in the Helmholtz Association, Berlin, Germany.
Bert FlemmingWorking Group Integrative Kidney Physiology, Institute of Physiology, Charité-University Medicine Berlin, Berlin, Germany.
Erdmann SeeligerWorking Group Integrative Kidney Physiology, Institute of Physiology, Charité-University Medicine Berlin, Berlin, Germany. erdmann.seeliger@charite.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal tissue hypoperfusion and hypoxia are early key elements in the pathophysiology of acute kidney injury of various origins, and may also promote progression from acute injury to chronic kidney disease. Here we describe basic principles of methodology to quantify renal hemodynamics and tissue oxygenation by means of invasive probes in experimental animals. Advantages and disadvantages of the various methods are discussed in the context of the heterogeneity of renal tissue perfusion and oxygenation.This chapter is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This introduction chapter is complemented by a separate chapter describing the experimental procedure and data analysis.

Indexed as

HemodynamicsRenal CirculationAnimalsBiomarkersElectrodesKidneyLasersMonitoring, PhysiologicOxygenOxygen ConsumptionPerfusionSoftwareBiomarkersOxygenIn vivo methodsQuantitative invasive probesRenal hemodynamics and oxygenation

Identifiers

PMID33475996
PMCPMC9703258

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.