Evidence map›Paper›PMID 33475979›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2021

The Relationship Between Matrix Metalloproteinase-8 in After Birth Oral Fluid and Acute Histologic Chorioamnionitis in Preterm Delivery.

Soo Ran Choi, Taehee Kim, Yejeong Kim, Sugyung Jung, Suk Jin Choi

Abstract read
PubMed Publisher
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Soo Ran ChoiDepartment of Obstetrics and Gynecology, Inha University College of Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, South Korea. csran@inha.ac.kr.ORCID http://orcid.org/0000-0003-3371-9102
Taehee KimDepartment of Obstetrics and Gynecology, Inha University College of Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, South Korea.
Yejeong KimDepartment of Obstetrics and Gynecology, Inha University College of Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, South Korea.
Sugyung JungDepartment of Obstetrics and Gynecology, Inha University College of Medicine, Inha University Hospital, 27, Inhang-Ro, Jung-Gu, Incheon, 22332, South Korea.
Suk Jin ChoiDepartment of Pathology, Inha University College of Medicine, Inha University Hospital, Incheon, South Korea.
Inha University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevated concentration of matrix metalloproteinase-8 (MMP-8) in amniotic fluid is a known predictor of intra-amniotic inflammation and infection. The aim of this study was to determine the nature of the association between MMP-8 levels in oral fluid obtained immediately after birth and acute histologic chorioamnionitis (HCA) in preterm delivery. Oral fluid was collected from 93 consecutive preterm birth newborns between gestational weeks of 24 + 0 and 36 + 6. Concentrations of MMP-8 and interleukin-8 (IL-8) in after birth oral fluid were measured by ELISA. Acute HCA was defined as the presence of neutrophils infiltration into chorioamnionic membranes. Logistic regression analysis was used for the statistical analysis. MMP-8 concentrations in after birth oral fluid were significantly higher for women with acute HCA than for those without (median [range]; 68.3 ng/mL [0.06-12,479.6] vs. 10.2 ng/mL [0.06-1808.2], p = 0.002). A strong association was observed between MMP-8 and IL-8 levels (γ

Indexed as

AdultAmniotic FluidChorioamnionitisFemaleGestational AgeHumansMatrix Metalloproteinase 8Obstetric Labor, PrematurePregnancyPremature BirthRetrospective StudiesMatrix Metalloproteinase 8Histologic chorioamnionitisMatrix metalloproteinase-8Oral fluidPreterm birth

Identifiers

PMID33475979
OpenAlexW3125829579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.