ArticlePhysical and engineering sciences in medicine2021
Dependence of the heating effect on tissue absorption coefficient during corneal reshaping using different UV lasers: A numerical study.
Article in Physical and engineering sciences in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Modeling of the laser linear thermal effects on the anterior and posterior layers of the human eye with and without thermoregulation.Lasers in medical science · 2025Article
- Evaluating the efficacy of Nd:YAG fourth harmonic (266 nm) in comparison with ArF excimer (193 nm) in laser corneal reshaping: ex vivo pilot study.International ophthalmology · 2023Article
- Human cornea thermo-viscoelastic behavior modelling using standard linear solid model.BMC ophthalmology · 2023Article
- Tissue engineering modalities in skeletal muscles: focus on angiogenesis and immunomodulation properties.Stem cell research & therapy · 2023Review
- Early cancer detection using the fluorescent Ashwagandha chitosan nanoparticles combined with near-infrared light diffusion characterization: in vitro study.Lasers in medical science · 2023Article
- A modified source-detector configuration for the discrimination between normal and diseased human breast based on the continuous-wave diffuse optical imaging approach: a simulation study.Lasers in medical science · 2022Article
- Assessing the local temperature of human cornea exposed to surface ablation by different laser refractive-surgery devices: a numerical comparative study.Lasers in medical science · 2021Article
- Nd:YAG fourth harmonic (266-nm) generation for corneal reshaping procedure: An ex-vivo experimental study.PloS one · 2021Article
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Authors and funding
4 authors.
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Abstract
Corneal reshaping using laser ablation effect is a well-known ophthalmologic operation implemented to correct many vision disorders. UV pulsed lasers are utilized in this surgery due to their high absorption in corneal tissue without affecting the other parts of the eye. Ideally ablation may not be associated with heat transport, since high temperature is the enemy of soft tissues. However, the thermal effect of this procedure can cause tissue damage if the temperature rises above the safety level without appropriate handling. In the present study, we try to find the trade-off between efficient ablation and minimal temperature rise. So the thermal effect on the corneal tissue after applying five UV wavelengths; 193, 210, 213, 223 and 248 nm has been simulated and investigated by solving Penne's bio-heat transfer equation using the finite element method. A 3D model of the human cornea is constructed using COMSOL Multiphysics computer software and the temperature rise is determined at the end of the laser pulse. The same spot size and pulse duration are used for each wavelength. While the absorption coefficient of the corneal tissue is the only variable as it is a wavelength dependent. The proposed results show that, the heating effect is directly proportional to the absorption coefficient. The highest recorded temperature was 259 °C at 193 nm, while, the minimum value was (70.1 °C) recorded at 248 nm at which the cornea has the lowest absorption coefficient.
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